Bisphosphonates are commonly used drugs for the prevention of osteoporotic fractures. In recent years, consumption has long been linked with the emergence of low-energy fractures of the femur with a characteristic transverse line. To evaluate this relationship we have analyzed the femur fractures treated low energy in our center for 2 years and related to the prior use of bisphosphonates. In subtrochanteric fractures, no significant differences were found; in diaphyseal fractures are typically transverse line is present in younger patients and significantly associated with prior use of bisphosphonates (6 of 8 thought this type fractures history of prolonged use of these drugs). In conclusion, although there have been numerous articles in the last years series of cases this type of fracture associated with prior use of bisphosphonates, the sample size of studies and the difficulties of assessing a drug consumption retrospective studies are needed prospective randomized to leave evidence of the possible association.
Ortego Sanz, J. ; Barrés Carsi, Mariano ; Balfagón Ferrer, A. ; Escribá Urios, I. Bifosfonatos y fracturas femorales de baja energía: la experiencia en nuestro centro. En: Revista española de cirugía osteoarticular, 2011, Volumen 46, Número 247: 141-145
