Evaluación de la capacidad de un nuevo colutorio de inhibir la formación del cálculo dental supragingival

Introduction: Dental calculus is a problem for oral health because it increases the accumulation of plaque and bacterial toxins and this causes the progression of periodontal disease. Objectives: The aim of this paper is to study the magnitude of dental calculus formed upon the use of a mouthrinse based on pyrophosphates and analyze their effectiveness and adverse effects on various aspects of the oral cavity. Material and Methods: This study it´s a randomized clinical trial and double-blind crossover. All individuals used a mouthrinse B (pyrophosphates) and a mouthrinse A (placebo) with the same organoleptic properties. General variables were recorded, salivary parameters (flow, pH and composition of saliva), a microbiological sample of subragingival plaque, magnitude of calculus formed was measured (Volpe-Manhold index, weight and volume), soft and hard tissues were analyzed and perception of mouthrinses by the patients. Results: Calcium, salivary flow and the pH tended to increase over the test B mouthrinse; but without significative differences between mouthrinse A and B. For the sodium, chloride and potassium, no reaction was influenced by the two mouthrinses and other like urea, uric acid and phosphorus, tended to decrease, but this alteration was similar for both mouthrinses. The microbiological analysis of supragingival plaque revealed that in terms of prevalence and absolute load, mouthrinses didn´t induced significant variations in bacterial species studied. For the measuring parameters, the magnitude calculus decreased significantly with mouthrinse test B from baseline to final measurement, although the decrease of volume was a similar for test and placebo. The moutrinses didn´t produced adverse effects and mouthrinse test B was perceived as the most effective. Discussion: The methodology used for this study could not be compared with other studies because it has never been made in others. The results corroborate the effectiveness of pyrophosphate in the decrease of dental calculus reflected in previous studies, but with this new formulation the results were better tan in the other studies. Conclusions: The test and placebo mouthrinses change certain parameters in the chemical composition of the saliva, emphasizing the decreased of urea, uric acid and phosphorus. Calcium, salivary flow and pH increase after the use test mouthrinse. The use of mouthrinse doesn´t change microbiological aspects. The mouthrinse test decreases significantly the calculus formed reflected in the VM index and weight. No alterations in teeth and soft tissue were observated after the use of the mouthrinses. There was good tolerance of mouthwashes by patients and mouthrinse test was perceived as more effective.