Journal of Clinical and Experimental Dentistry. 2023. Vol. 15, no. 11

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    The use of cone beam computed tomography by brazilian endodontists: A questionnaire-based survey
    (Medicina Oral S.L, 2023) Paiva, Hermano-Camelo; Akisue, Eduardo; Ferreira, Felipe-Potgornik; Matos, Karla-Nogueira; Al Zaibak, Hasan; Scardini, Iandara-de Lima; Caldeira, Celso-Luis; Candeiro, George-Táccio-de Miranda; Gavini, Giulio
    BACKGROUND: This study aimed to assess the knowledge of Brazilian endodontists regarding the use of cone beam computed tomography (CBCT) in endodontic therapy. MATERIAL AND METHODS: An invitation to participate in the research was sent to 3256 professionals through class groups on social networks and via email. Participants answered an online questionnaire consisting of 11 questions about the clinical situations in which they used CBCT and whether they had any knowledge of the technical protocols such as parameters of field of view (FOV) and voxels of the CBCT equipment. The questionnaire was answered by 742 endodontists who represented 22.7% of the invited professionals. RESULTS: The data obtained indicate that 76.7% of the participants use or have used CBCT during endodontic treatments. The most often reported clinical conditions for using the CBCT were: root fractures (64%), locating the canals (58.7%), perforations (53.9%), and root resorption (42.1%). More than 60% of the participants stated that they do not have information about the voxel, FOV, and the CBCT system used in their requests. Only 34.1% reported using CBCT to the performed endodontic treatments follow-up. CONCLUSIONS: CBCT was a tool widely utilized by the participants, with root fracture being the clinical condition with the highest indication for CBCT. Many professionals were unaware of the technical protocol used in the exams. Key words:Endodontics, Cone Beam Computed Tomography, Endodontic Therapy.
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    Bibliometric study of the systematic reviews and meta-analyses in dentistry
    (Medicina Oral S.L, 2023) Tarazona Álvarez, Beatriz; López Roldán, Andrés; Vidal Infer, Antonio Martín; Alonso Arroyo, Adolfo
    BACKGROUND: Scientific production has increased in the last decades, consequently the number of systematic reviews, reviews and meta-analyses, the objective is to carry out a bibliometric analysis study of systematic reviews and meta-analyses in dentistry, divided into different thematic areas. MATERIAL AND METHODS: A search was conducted in the Science Citation Index-Expanded on the core collection of Web of Science, they were selected from the area of Dentistry and Oral Surgery and Medicine categories, the data was downloaded on April 20, 2022 and The 100 most cited articles from each of the thematic areas were selected. RESULTS: An increase in this type of articles was observed in the last decade in the areas of pediatric and medical dentistry and oral pathology. The thematic area that received the most citations was periodontics. The two authors with the most citations are Zwahlen, Marcel and Pjetursson, Bjarni Eluar. The countries that receive the most citations are European, along with the USA and China. The topics that are most published in this type of article deal with Cancer with 50 publications, caries treatment with 25 and fluoridation with 1. The entities that finance this type of articles the most are private companies (26.76%). CONCLUSIONS: Together with an exponential increase in the number of publications in dentistry, there has been an increase in the number of publications in systematic reviews. The areas publishing the most articles and having the most citations are Periodontics and Implantology, despite the fact that the most studied topic is cancer. Key words:Bibliometrics, methodological study, systematics reviews, metanalys.
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    Effect of oral hygiene in infants before dental eruption on Candida spp. colonization and the occurrence of oral candidiasis: A randomized clinical trial
    (Medicina Oral S.L, 2023) Lopes, Ana-Beatriz-Silva; Cardoso, Valeria-Macedo; Moreira, Luana-Viviam; Ramos-Jorge, Joana; Ramos-Jorge, Maria-Letícia; Fernandes, Izabella-Barbosa
    BACKGROUND: To assess the influence of oral hygiene in infants before the primary tooth eruption on colonization by Candida spp. and the occurrence of oral candidiasis. MATERIAL AND METHODS: Fifty-six infants were randomly selected in their first 48 hours of life and allocated into 2 groups: Group I (Mothers were instructed to sanitize the oral cavity of the infant with gauze and filtered water once a day) and Group II (Mothers were instructed not to sanitize the oral cavity of the infant before the dental eruption). Data collection was performed one month after the birth of the infant, in their residence, including saliva collection for identification and quantification of Candida spp. RESULTS: Colonization by Candida spp. species was found in 49.1% of the infants evaluated. There was no statistically significant difference between colonization by Candida spp. and intervention groups (p=0.947). 13.2% of the participants presented oral candidiasis during the first month of life, this prevalence was 15.4% in the control group and 11.1% in the intervention group, however, this difference was not significant (p=0.704). CONCLUSIONS: The Candida spp. colonization and the oral candidiasis occurrence, in the first month of the life of the infant, were not influenced by oral hygiene. Key words:Infants, oral hygiene, oral health, oral candidiasis.
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    Assessment of Oral Health Status in a Prison Population in Northern Portugal
    (Medicina Oral S.L, 2023) Soares, Mariana; Gonçalves, Maria; Rompante, Paulo; Salazar, Filomena; Monteiro, Luís; Pacheco, José-Júlio; Relvas, Marta
    BACKGROUND: Prisoners constitute one of the disadvantaged groups and it is observed that these individuals suffer from poor oral hygiene and the prevalence of oral diseases is higher compared to the general population. MATERIAL AND METHODS: The aim of this study is to assess the state of the oral health in a prison population in Northern Portugal. A cross-sectional observational study was conducted involving 103 male prisoners with age between 25 and 75 years old. A questionnaire was presented to all the prisoners and an intraoral clinical examination was performed in each of them. RESULTS: The sample mean age was 41.58 ± 8.94 years. Most participants consume sugary foods, with 32% consuming then on a daily basis. It was noticed that 13.6% of the participants do not brush their teeth. Most of the prisoners smoke (78.6%) and 70 smoke more than 10 cigarettes per day. The mean DMFT was 17.17 ± 8.23 and the component with the highest weight was the number of missing teeth, with a mean value of 13.14 ± 8.32. It was observed that 7 individuals are edentulous and 64 (62.1%) have caries lesions. It has been noted that of the 64 individuals presenting caries lesions, 47 (73.4%) eat sugary foods, however this relationship is not statistically significant. It was found that the prevalence of periodontal health was 26%, gingivitis was 32.3% and periodontitis was 41.7%. Plaque Index was evaluated according to the periodontal condition, it was observed a significantly lower level of plaque index in the periodontally healthy subjects compared to the subjects with gingivitis and the subjects with periodontitis. CONCLUSIONS: The prevalence of oral diseases in this prison population is high, as is the loss of teeth. Dental caries is the most observed oral disease, and periodontitis the most common of the periodontal diseases. Key words:Prisoners, Oral health, Caries, DMFT, Periodontitis, Oral diseases.
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    Influence of root fragility and irrigation on external root temperature variation during preparation for fiberglass posts
    (Medicina Oral S.L, 2023) Göhringer, Isabella; Giacomel, Maria-Cecília-Lopes; Filho, Flares-Baratto; Magão, Pedro-Henrique; Furuse, Adilson-Yoshio; Furuse, Gisele-Aihara-Haragushiku; Gonzaga, Carla-Castiglia
    BACKGROUND: This paper analyses the effects of root canal fragility and irrigation on external temperature change (ΔT) of different sections of roots during post-space preparation. MATERIAL AND METHODS: Forty endodontic treated human premolars were evaluated. Roots were divided into four groups based on their root wall thickness (fragile or non-fragile), and whether they received irrigation (yes or no) during post-space preparation. Initial root canal temperature was kept at 37°C. ∆T was evaluated with thermistors attached to the cervical and apical thirds of the roots during two preparation steps: 1) removal of gutta-percha with Largo drills, and 2) using the specific drill for post-space preparation for cementation of fiber-reinforced posts. In the irrigated groups, we used a 2% chlorhexidine solution during the exchange of drills. ∆T data was analyzed using four-way ANOVA with repeated measures and Tukey's test (α = 0.05). RESULTS: Significant differences in ∆T based on root fragility (p = 0.017), root canal third (p = 0.013), and preparation step (p = 0.006). We found that non-fragile roots tended to have higher ∆T than fragile roots, particularly in the apical third, during the use of the second drill. Irrigation did not have a significant effect on temperature variation, regardless of root wall thickness or the third evaluated (p> 0.05). CONCLUSIONS: Findings suggest that root wall thickness and the third evaluated influence temperature changes during post-space preparation for cementation of posts. Non-fragile roots showed greater temperature variation than fragile roots, while irrigation did not significantly impact temperature changes. Key words:Temperature, post and core technique, tooth preparation.
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    Evaluation of the apical sealing of an eggshell hydroxyapatite-based sealer
    (Medicina Oral S.L, 2023) Fontana, Carlos-Eduardo; Dos Santos, Beatriz-Anjos; Campos, Mônica-Celes-Nascimento-Machado; de Lima, Samara-Gonçalves-Félix; da Silva, Venâncio-Castro; Gonçalves, Aline-Dentini-Luque; de Moura, João-Daniel-Mendonça; Rocha, Daniel-Guimarães-Pedro; Pinheiro, Sérgio-Luiz; Bueno, Carlos-Eduardo-da Silveira
    BACKGROUND: The success of endodontic treatment can be influenced by the type of endodontic sealer used, as certain sealers may be prone to apical microleakage, leading to treatment failure. The limitations of currently available sealers necessitate the development of new materials to improve the success rate of endodontic treatment. Therefore, the objective of this study was to assess the apical microleakage of newly developed hydroxyapatite-based endodontic sealers, including one derived from eggshells, and compare them with other commercially available sealers. MATERIAL AND METHODS: Eighty-five extracted human upper anterior teeth were selected for this study. The teeth were divided into 5 experimental groups and 2 control groups. The experimental groups were designated as follows: (1) HPSINT - obturated with gutta-percha cone and synthetic hydroxyapatite-based sealer, (2) BIOC - obturated with gutta-percha cone and Bio C-Sealer sealer, (3) AHPLUS-BC - obturated with gutta-percha cone and AHPLUS Bioceramic sealer, (4) AHP - obturated with gutta-percha cone and AHPLUS sealer, and (5) HPO - obturated with gutta-percha cone and sealer based on hydroxyapatite extracted from eggshells. Additionally, there were positive and negative control groups consisting of instrumented teeth filled with gutta-percha cones without any sealer and instrumented teeth without any filling, respectively. Methylene blue dye penetration was used to assess apical microleakage. Descriptive statistical analysis and Shapiro-Wilk normality test were applied to the observed results. As the samples followed a normal distribution, the ANOVA test was applied. RESULTS: The control groups confirmed the validity of the experimental method, while the experimental groups showed varying degrees of dye penetration. The group obturated with Bio C-Sealer exhibited the highest mean apical microleakage, while AHPLUS Bioceramic sealer demonstrated lower mean than AHPLUS sealer and sealer based on hydroxyapatite extracted from eggshells (p0.05). No significant difference was observed between the hydroxyapatite-based sealers and the AHPLUS-BC sealer. CONCLUSIONS: The results of this study suggest that the newly developed hydroxyapatite-based endodontic sealers, including the one derived from eggshells, may have a lower risk of apical microleakage compared to other commercially available sealers. These findings highlight the potential of hydroxyapatite-based sealers to improve the success rate of endodontic treatment. Further research and clinical studies are warranted to validate these results and explore the long-term effects of these novel sealers. Key words:Endodontic treatment, apical microleakage, endodontic sealer, hydroxyapatite, eggshell-derived sealer.
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    Influence of concentration, irrigation method, and root canal third on intratubular penetration of sodium hypochlorite - a broad statistical analysis
    (Medicina Oral S.L, 2023) Machado, Ricardo; Nantes, Breno; Guimarães, Diego-Augusto; Reinke, Stella-Maria-Glaci; Back, Eduardo-Donato-Eing-Elgelke; Comparin, Daniel; Ignácio, Sérgio-Aparecido; Vansan, Luiz-Pascoal
    BACKGROUND: The permanence of microorganisms in the root canal system represents the main cause of endodontic failure. Considering the impossibility of effective action of the endodontic files in ramifications of the main canal and mainly inside the dentinal tubules, a better understanding of the irrigation dynamics to enhance endodontic prognosis is essential. Objective: To evaluate the depth of intratubular penetration values of sodium hypochlorite (NaOCl) (dependent variable) by comparing different concentrations, methods of irrigation, and root canal thirds (independent variables) and to investigate the existence of interactions among them, capable of influencing the dependent variable. MATERIAL AND METHODS: 40 roots from extracted human maxillary central incisors were stained and instrumented according to four irrigation protocols (n. 10): conventional irrigation (CI) at each use or change of instrument, and final irrigation with 5ml of 2.5% or 5.25% NaOCl, with or without passive ultrasonic irrigation (PUI), respectivelly. Measurements based on stereomicroscopic images were obtained, and the data were subjected to statistical analysis (p< 0.05). RESULTS: The highest depth values of intratubular penetration of NaOCl were observed in the cervical third, at 5.25%, and by PUI. When only two independent variables were analyzed in association, the highest penetration depth values of NaOCl were obtained at 5.25%, regardless of irrigation method, at 5,25%, in the cervical third, and; in the cervical third, despite of irrigation method. Considering the three independent variables simultaneously, the highest depth values of intratubular penetration of NaOCl were observed in the cervical third, at 5.25%, no matter the irrigation method. The interaction between the independent variables on the penetration depth values of NaOCl was only confirmed considering the irrigation method and root canal third. CONCLUSIONS: Intratubular penetration of NaOCl was influenced by the three independent variables individually and when the irrigation method and root canal third were considered simultaneously. Key words:Dentinal tubules, Depth, Disinfection, Irrigation, Root canal system, Sodium hypochlorite.
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    Short Implant and Heavy Smokers as Predictors for Failure of Immediate Implants: a Retrospective Study
    (Medicina Oral S.L, 2023) da Silva, Alexandre-Marques-Paes; da Silva, Ana-Paula-Marques-Paes; Vieira, Mayra-Stambovsky; Canabarro, Antônio; Gonçalves, Lucio-Souza; Ferreira, Dennis-de Carvalho
    BACKGROUND: The possibility of installing implants in fresh sockets was first proposed as a viable treatment option in the 1970s. Objective: to assess the relationships of subject-level and implant-level characteristics on the failure of immediate implants installed in sites that contained teeth associated or not with chronic apical periodontitis. MATERIAL AND METHODS: A retrospective study was undertaken with data from patients who received immediate implants with a minimum follow-up of 12 months after loading. The Generalized Estimating Equation, applying a multiple logistic regression model, was employed to investigate the association between predictor variables/co-variables and failure of the immediate implants. RESULTS: Four hundred and twenty-three implants were installed (208 uninfected/215 infected sites) in 186 patients (92 men/96 women) with a mean age of 57.1 years old. The survival rate of implants was 91%. Approximately half (215/50.8%) of the alveoli that received immediate implants had chronic apical periodontitis associated with the extracted teeth, and 191 (88.8%) of these survived until the last follow-up visit. When the infection-free sites were analyzed, this frequency was higher (93,3%), but the presence of chronic apical periodontitis did not show statistical significance in the implant failure (p=0.167). Smokers with a consumption of more than 20 cigarettes/day and short implants had more failures (OR:7.66, p=0.012; OR:14.06, p=0.002; respectively). CONCLUSIONS: Short implants and consumption of more than 20 cigarettes/day were important predictors for failure of immediate implants, regardless of presence of chronic apical periodontitis. Key words:Osseointegration, dental implant, smokers, study, immediate dental implant loading.
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    Nonsurgical treatment of an adult with skeletal Class III malocclusion, posterior crossbite and mandibular asymmetry
    (Medicina Oral S.L, 2023) Bellot Arcís, Carlos ; Ferrando-Magraner, Elena; Tarazona Álvarez, Beatriz ; García-Sanz, Verónica; Paredes Gallardo, Vanessa
    Class III malocclusion represents a very heterogeneous clinical condition that is characterized by the combination of a wide variety of skeletal and/or dental components. Given the wide diversity, diagnosis and treatment of such malocclusion has always been a challenge for clinicians. Despite the different treatment options available, the treatment approach in the adult patient must depend fundamentally on the patient's decision, guided by the orthodontist and the maxillofacial surgeon. This case report presents the treatment of a patient with Class III malocclusion, with posterior crossbite and anterior edge-to-edge bite with fixed appliances and skeletal anchorage, an interdisciplinary, nonsurgical approach for a skeletal malocclusion. Firstly, to improve the posterior transverse relationship a band-soldered compressed lingual arch was cemented to the mandibular first molars. Then, once a correct transverse relationship was achieved, two miniscrews were placed distal to the mandibular second molars to distalize the whole mandibular arch, and avoid excessive inclination of maxillary incisors to improve dentofacial esthetics. At the end of the treatment, all the objectives planned at the beginning had been achieved and remained stable after the retention period. Key words:Clase III, orthodontic treatment, distalizing, appliances, posterior crossbite.
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    Why choose articaine over lidocaine for the removal of third molars? Systematic review and meta-analysis
    (Medicina Oral S.L, 2023) Nogueira, Emerson-Filipe-de Carvalh; Almeida, Renata-de Albuquerque-Cavalcanti; de Souza, Bruno-Luiz-Menezes; Aguiar, Priscila-Lins; Vasconcellos, Ricardo-José-de Holanda
    BACKGROUND: The aim of the present study was to seek scientific evidence through a systematic review and meta-analysis for the choice of articaine over lidocaine in the removal of third molars. MATERIAL AND METHODS: Searches were performed of the MEDLINE/PubMed, EMBASE, Cochrane Library (CENTRAL), Web of Science, and SCOPUS databases as well as the grey literature. RESULTS: Four hundred three articles were found, only 14 of which met the eligibility criteria. A total of 1114 third molars were removed: 557 with articaine and 557 with lidocaine. Articaine had a higher success rate than lidocaine (RR = 1.09, 95% CI: 1.03 to 1.15; P< 0.05), shorter subjective latency time (MD = -15.10, 95% CI: -21.57 to -8.63; P< 0.05), less intraoperative pain (MD = -6; P< 0.05), longer duration (MD = 68.86; P< 0.05), and less postoperative pain (MD = -3.05; P< 0.05). CONCLUSIONS: Based on the findings, articaine is superior to lidocaine for use in lower third molar surgeries due to the higher success rate, shorter time until the onset of action, greater control of intraoperative and postoperative pain, and longer duration of the anesthetic effect. Key words:Articaine, lidocaine, third molar, impacted teeth.
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    Performance of artificial intelligence using cone-beam computed tomography for segmentation of oral and maxillofacial structures: A systematic review and meta-analysis
    (Medicina Oral S.L, 2023) Abesi, Farida; Hozuri, Mahdi; Zamani, Mohammad
    BACKGROUND: There are different values reported about the performance of artificial intelligence using cone-beam computed tomography (CBCT) for segmentation of oral and maxillofacial structures. We aimed to perform a systematic review and meta-analysis to provide an overall estimate to resolve the given conflicts. MATERIAL AND METHODS: A literature search was conducted in Embase, PubMed, and Scopus through 31 October 2022, to identify studies evaluating artificial intelligence systems using oral and maxillofacial CBCT images for automatic segmentation of anatomical landmarks. The surveys had to report the outcome according to dice coefficient (DICE) or dice similarity coefficient (DSC) index. The estimates were presented as percent and 95% confidence interval (CI). I-squared index was used to assess the heterogeneity between the surveys. RESULTS: A total of 24 eligible studies were finally enrolled. The overall pooled DICE/DSC value for artificial intelligence was 0.92 (95% CI: 0.88-0.95; I-squared=93.6%, p<0.001). Tooth and mandible were evaluated more than other anatomical regions (five studies for each one). The lowest and highest DICE/DSC scores for the artificial intelligence related to inferior alveolar nerve (0.55 [95% CI: 0.47-0.63]) and pharyngeal airway and sinonasal cavity (0.98 [95% CI: 0.98-1.00]). CONCLUSIONS: The findings revealed excellent performance for the artificial intelligence regarding the segmentation task of oral and maxillofacial CBCT images. Key words:Artificial intelligence, cone-beam computed tomography, segmentation performance, dentistry.
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    Does Diabetes Increase the Frequency of Root-Filled teeth: Systematic Review and Meta-Analysis of Observational Studies
    (Medicina Oral S.L, 2023) León-López, María; Cabanillas-Balsera, Daniel; Martín-González, Jenifer; Chandler-Gutiérrez, Lucy J.; Areal-Quecuty, Victoria; Montero-Miralles, Paloma; Crespo-Gallardo, Isabel; Segura-Egea, Juan J.
    BACKGROUND: The indicated treatment in cases of apical periodontitis (AP), a disease very prevalent in diabetic patients, is root canal treatment (RCT). This study aims to conduct a systematic review with meta-analysis to answer the following PICO question: In adult patients, does the absence or presence of diabetes affect the prevalence of root filled teeth (RFT)"? MATERIAL AND METHODS: PRISMA Guidelines have been followed to carry out this systematic review. A literature search was undertaken in PubMed-MEDLINE, Embase and Scielo. All studies reporting the prevalence of RFT in diabetic patients and control subjects using radiographic examination were included. Study characteristics and risk ratios with 95% CIs were extracted. Random-effects meta-analyses were performed. RESULTS: Five studies fulfilled the inclusion criteria. Prevalence of RFT were estimated with 701 people and 15,882 teeth. Among diabetic patients, 6.1% of teeth had undergone RCT, while in controls this percentage was 3% (OR = 1.7; 95% CI = 1.0 - 2.9; p = 0.065). Among diabetic patients, 65% had at least one RFT, while in controls this percentage dropped to 55% (OR = 1.4; 95% CI = 0.5 - 3.7; p> 0.05). The certainty of evidence was low. CONCLUSIONS: The prevalence of RFT in diabetic patients is almost double that in the control population, however this result is only marginally significant. Dentists must take into account the high prevalence of RFT in diabetic patients, investigating the presence of diabetes in those patients in whom a high frequency of RCT is observed. Key words:Diabetes, endodontics, epidemiology, root canal treatment, root filled teeth, prevalence, survey, population-based study.