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Language Journal of Clinical and Experimental Dentistry. 2023. Vol. 15, no. 06
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- Application of 5-Fluorouracil in management of glandular odontogenic cyst(2023) Titinchi, Fadi; Thompson, Junaid; Ranchod, SanjayGlandular odontogenic cyst (GOC) is a rare, aggressive odontogenic lesion that presents in the jaws. It is a diagnostically challenging entity due to its ability to mimic intraosseous mucoepidermoid carcinoma, botryoid cyst, surgical ciliated cyst, and radicular cyst. Treatment ranges from conservative to aggressive surgical interventions due to its varied clinical and radiological appearance and also its potential for recurrence. Aggressive surgical interventions result in the need for surgical site reconstruction, thus increasing patient morbidity. We report a case of GOC in the anterior mandible that was conservatively treated by the application of 5-Fluorouracil (5-FU). Topical application of 5-FU was selected in the management of this lesion as it has shown to be effective in reducing recurrence rates of other aggressive odontogenic lesions such as odontogenic keratocysts. To our knowledge, this is the first case reported in the literature that was successfully treated by the combination of cyst enucleation, curettage, peripheral ostectomy and application of 5-FU. No recurrence was detected after 14-month follow-up.
- Efficacy of transcutaneous electrical nerve stimulation (TENS) in the management of trigeminal neuralgia: a systematic review and meta-analysis(2023) Motwani, Mukta B.; Fadnavis, Aditi; Dhole, ApekshaTrigeminal Neuralgia is one of the most painful disorders known to man. So making patient pain free and to achieve a better quality of life in TN patients is one of the biggest challenge. Non-invasive procedures like Transcutaneous electrical nerve stimulation (TENS) have been tried clinically for Trigeminal neuralgia. Aim: The systematic review and meta-analysis aimed to compare and evaluate the efficacy of transcutaneous electric nerve stimulation in the management of trigeminal neuralgia. The present review has been registered with PROSPERO – An international prospective register of systematic review CRD42021254136.An electronic search was done in PubMed, Cochrane Library, Science Direct, Google Scholar, EBSCOHOST. The assessments of articles were done using selection criteria and PRISMA guidelines Only prospective clinical trials like Randomized clinical trials (RCTs) and clinical trials were included in this review. A total of three studies were included in the meta -analysis, The proportion of total number of patients after TENS therapy across studies with p-value < 0.0001 for each which showed statistically significance. The overall difference in two groups was significant with standardize mean difference of 3.03 [95% CI: 2.50, 3.56].TENS can be an effective treatment modality for trigeminal neuralgia in reducing the pain intensity with no reported side effects for patients with trigeminal neuralgia alone or even in combination with other first line drugs.
- Gingival lymphatic malformation. An atypical case report(2023) Alberdi Navarro, Javier; Ruiz-Ochoa, Nerea; Juan Galíndez, A. de; Uribarri Etxebarría, AgurneLymphatic malformations are a rare pathology that presents a highly variable clinical expression. Intraorally, it mainly affects the dorsum of the tongue. The objective of this work is to present a case of lymphatic malformation in an atypical location. A 20-year-old male who attended the clinic for multiple vesicular lesion in attached gingiva, asymptomatic and of unknown evolution. Removal of the lesion and subsequent histological analysis were performed, which showed a microcystic lymphatic vascular lesion. Immunohistochemistry for D2-40 was performed, which corroborated the lymphatic origin of the lesion. At 6 months, no recurrence of the lesion was recognized. Clinicians should include lymphatic malformations in the differential diagnosis of multiple vesicular lesions. Knowing the oral manifestations of this entity is essential for its proper diagnosis and clinical management.
- Disinfection of the air and surfaces in the dental clinic using hydroxyl radical (OH-) based technology: a systematic review(2023) Paños-Crespo, Anais; Traboulsi-Garet, Bassel; Sánchez-Garcés, María Ángeles; Gay-Escoda, CosmeA systematic review was carried out to compare the disinfectant capacity of hydroxyl radicals (OH-) versus other products commonly used for disinfecting the air and surfaces.A literature search was made of the Cochrane Library, PubMed (MEDLINE) and Scopus databases. “In vitro” studies evaluating disinfection methods applicable to several surfaces and room air were included in the search. The search was carried out in April 2022, with no restrictions in terms of language or publication date.Of the 308 articles identified from the initial search, 8 were included for the quantitative analysis. All publications corresponded to experimental “in vitro” studies. Seven of them evaluated biocidal action against bacteria, and only two assessed activity against viral loads. The generation of contaminants secondary to application of the disinfectants was only analyzed in one of the studies, with the conclusion that the production of peroxyl radicals (RO2) derived from the oxidation of volatile organic compounds (VOCs) is greater when chemical surface disinfectants are used versus air disinfection systems.The disinfection capacities of the currently available methods are similar, and none of them are able to replace the use of additional physical protection measures.
- Prevalence of pulp and periapical diseases in the endodontic postgraduate program at the national autonomous University of Mexico 2014-2019(2023) Pérez, Andrea-Soledad-Sepúlveda; Bolado, Enrique-Chávez; Camacho-Aparicio, Liliana A.; Hervert, Luis-Pablo-CruzInvestigations on the prevalence of pulp and periradicular diseases in Mexican population produced few studies, conducted to specific age population. Considering the importance of epidemiological investigation.The aim of this study was to estimate the prevalence of pulp and periapical pathologies and their distribution according to sex, age, affected teeth, and etiological factors found in patients the DEPeI, FO, UNAM Endodontic Postgraduate Program during the period 2014–2019.The data collected were from the records of the Single Clinical File of patients treated at the Endodontic Specialization Clinic, DEPeI, FO, UNAM, period 2014–2019. The following variables were recorded for each endodontic file: diagnosed pulp and periapical pathology, sex, age, affected tooth, and etiological factor. Descriptive statistical analysis was performed with 95% CI (Confidence intervals).Of all the registers reviewed, irreversible pulpitis (34.58%) and chronic apical periodontitis (34.89%) proved to be the most prevalent pulp and periapical pathologies, respectively. The female sex predominated (65.36%). The age group that requested the most endodontic treatment, according to the records reviewed, was 60 or older (36.99%). The most treated teeth were the upper first molars (24.15%) and lower (36.71%), and the most prevalent etiological factor was dental caries (84.07%).Irreversible pulpitis and chronic apical periodontitis were the most prevalent pathologies. The predominant sex was female, and the age group was 60 years or older. The first upper and lower molars were the most endodontically treated teeth. The most prevalent etiological factor was dental caries.
- Influence of the third molar presence on the thickness and height of the buccal cortical bone of the mandibular first and second molars(2023) Pinheiro, Paulo-Márcio-de Mendonça; Freitas, Karina-Maria-Salvatore; de Castro, Renata-Cristina-Faria-RibeiroThis study aimed to evaluate the influence of the presence of the third molars on the thickness and height of the buccal cortical bone of the first and second mandibular molars.The retrospective cross-sectional observational sample consisted of 102 CBCTs of patients (mean age of 29 years), divided into two groups: G1: 51 patients (26 female; 25 male, mean age of 26 years) presenting the mandibular third molars and G2: 51 patients (26 female; 25 male, mean age of 32 years) with the absence of the mandibular third molars. The total and the cortical depth were evaluated at 4 and 6mm from the cementoenamel junction (CEJ). The total thickness of the buccal bone was evaluated in two horizontal reference lines located apically 6 mm and 11 mm from the CEJ. Statistical comparisons were performed with Mann Whitney and Wilcoxon tests.In the comparison of buccal bone thickness and height between the groups, there was a statistical difference in tooth 36. In tooth 37 there was a statistical difference in the mesial root. For tooth 47, there was a statistical difference for the total thickness at 6mm, 11mm and 4mm. Concerning age, there was a tendency to decrease the values of these variables with increasing age.The mean values for buccal bone thickness, total and cortical depth of the mandibular molars were higher for patients with mandibular third molars because the buccal bone thickness of the mandibular molars increased in the posterior and apical direction.
- León (Spain) Health professionals’ knowledge and clinical practice towards the relationship between cardiovascular diseases and periodontal disease(2023) Gómez-González, Juan-Manuel; del Canto-Díaz, Mariano; Jacobo Orea, Clara; Alobera Gracia, M. A.; Canto Pingarrón, Mariano delCardiovascular pathologies have a high prevalence in the geriatric population, with acute myocardial infarction being one of the main causes of death in Spain. These pathologies have a systemic inflammatory component that is of vital importance. We also know in dentistry that the main gingival pathogens are capable of generating a systemic inflammatory response, being indirectly involved in the development of the atherosclerotic lesion, assuming, therefore, that periodontal disease is a cardiovascular risk factor. The objective of this study is to determine the knowledge of health professionals who treat cardiovascular diseases about periodontal disease and its relationship with heart disease.A health survey was carried out on 100 Cardiologists, Internists and General Practitioners in the province of León. Points of interest in this survey: the professional’s own oral health, knowledge of the relationship between periodontal and heart disease and, lastly, the training received in medicine on oral health.60% of professionals reviewed their oral health annually and 20% randomly. 48% of health professionals were unaware of periodontal diseases, 77% claimed to have not received university training in this regard, only 13% of those surveyed acknowledged having received more than 10 hours of training on oral health in their experience and finally, 90% thought that training in both Medicine and Dentistry should be collaborative.The degree of knowledge of health professionals regarding oral health is poor (77%), therefore the number of collaborative consultations with dental professionals is low (<63%). Training projects targeting a correct preventive medicine are shown to be necessary.
- Roughness assessment of colored compomers: results after an erosive-abrasive in vitro cycling test(2023) Magalhães, Louise; Belém, Fernanda-Vieira; França, Kamilla; Assunção, Cristiane-Meira; Martins-Júnior, Paulo-Antônio; Turrioni, Ana-Paula; Paschoal, Marco-Aurélio-BeniniThe present in vitro study aimed to evaluate and compare the surface roughness of a colored compomer and a composite resin, after 15 days of erosive-abrasive cycling. The sample included ninety circular specimens, randomly divided (n = 10): G1 Berry, G2 Gold, G3 Pink, G4 Lemon, G5 Blue, G6 Silver, G7 Orange and G8 Green, referring to the different colors of compomer (Twinky Star®, VOCO, Germany) and G9 for composite resin (Z250®, 3M ESPE). The specimens were submerged in artificial saliva and stored at 37°C for 24 hours. After polishing and finishing, the specimens were submitted to initial roughness (R1). Then, the specimens were submerged in an acidic cola-based drink for 1 minute and then exposed to electric toothbrushing for 2 minutes for 15 days. After this period, the final roughness (R2) and the ΔRa were performed. Data were submitted to ANOVA and Tukey’s test for intergroup comparison and paired T-test for intragroup comparison (p<0.05). Among compomers, the green color presented the higher/lower initial and final roughness values (0.94 ± 0.44, 1.35 ± 0.55) with lemon color presenting the most prominent real roughness increase (ΔRa = 0,74) whereas composite resin showed the lower values (0,17 ± 0.06, 0,31 ± 0.15; ΔRa = 0,14). All compomers, after the erosive-abrasive challenge, presented an increase in roughness values when compared to composite resin with a highlight to green tones.
- Comparative physical and mechanical properties of a 3D printed temporary crown and bridge restorative material(2023) Rizzante, Fabio A. P.; Bueno, Tamires; Guimarães, Genine; Moura, Guilherme; Teich, Sorin; Furuse, Adilson Yoshio; Mendonça, GustavoThe objective was to compare physic-mechanical properties of different materials used for temporary restorations.Protemp 4/bisacrylic resin, Jet/acrylic resin, and Nexdent C&B/3D-printed resin samples (10mm diameter x 2mm thickness) were analyzed for surface roughness and color stability tests (baseline, after 5 thousand brushing cycles; and after artificial aging in water at 60oC for 24 hours) and Knoop microhardness. All data were checked for normality using Shapiro-Wilk test. Surface roughness and color stability were analyzed using two-way repeated measurements ANOVA, microhardness data was subjected to one-way ANOVA. All tests were followed by Tukey test and were performed with α=0.05.For roughness, material (p=.002), time points (p=.002) and interaction between both (p<.001) were significant. All groups presented similar roughness for measurements of baseline and after brushing. After artificial aging, 3D printed resin showed decreased roughness when compared with other resins, and with its baseline reading. Acrylic resin showed an increase in surface roughness (when compared with measurement after brushing cycles). Considering color stability, only the material (p=.039) and the time (p<0.001) were significant. All groups showed similar color variation before and after artificial aging. There was an increase in color alteration after artificial aging for all groups. Considering microhardness test (p<.001), the 3D printed resin showed the highest values and acrylic resin the lowest. Bysacylic resin was similar to both 3D printed and acrylic resins.The tested 3D printed resins present similar or better properties than other tested temporary materials while being integrated with the digital workflow.
- Concordance of the facial biotype between Bjork-Jarabak cephalometrics and photographic analysis of the facial opening angle(2023) Medina-Grandez, Ana-Flavia; Llontop-Palma, Luciana; Ruíz-Mora, Gustavo-Armando; Rodríguez-Cárdenas, Yalil-Augusto; Aliaga-Del Castillo, Aron; Dutra, Vinicius; Arriola-Guillén, Luis-ErnestoAnalysis of the facial biotype can provide useful information for orthodontic diagnosis and can determine the type of growth of a patient to guide orthodontic treatment. The objective of this study was to determine the concordance of the facial biotype according to Bjork-Jarabak cephalometric analysis and photographic analysis of the angle of facial opening in Peruvian individuals.This retrospective study included 244 cephalometric radiographs and frontal photographs of the same patients obtained from a database. The facial biotype (mesofacial, brachyfacial, or dolichofacial) was determined with the Björk-Jarabak polygon (cephalometric) and the angle of facial opening (photographic). Two trained investigators performed all the measurements. The concordance of the facial diagnosis was determined using correlations of the interclass coefficient and the kappa test. p<0.05 In cases with a mesofacial biotype, both analyses coincided in 60 individuals (68.2%), while in those diagnosed with a dolichofacial biotype, the analyses only coincided in 17 individuals (10.4%). There was no concordance between the two methods regarding the brachyfacial biotype since according to the angle of facial opening none of the individuals presented a brachyfacial biotype (kappa weighted test= 0.020, p=0.586).Cephalometric and photographic analyses should be complementary and one should not substitute the other. Attention should be focused on dolichofacial and brachyfacial biotypes, which showed less concordance between evaluations. So, more studies are needed to follow this line of research.
- Ibuprofen intake after apicoectomy–Quantitative indicator for postoperative pain(2023) Arabadzhiev, Ivan; Nix, CarstenApicoectomy is one of the procedures that are most frequently performed by specialists in oral surgery. This paper presents an analysis of Ibuprofen consumption after apicoectomy and factors such as patient’s age, sex and type of resected tooth. Ibuprofen intake is treated as a quantitative indicator of pain sensation.The presented data cover 89 operations with 98 resected teeth. All those apicoectomies were performed by one and the same specialist in oral surgery and all patients were scheduled for a control examination on the day following the intervention. The reported Ibuprofen intake was recorded and analyzed afterwards.The mean number of consumed Ibuprofen 400 mg tablets, necessary to eliminate the pain was 1.71 (SD±1.33). Gender was not established as responsible for statistically significant differences. Poor negative statistical correlation was established between age and number of consumed tablets. Older patients used a smaller amount of analgesics. The intake after resection of mandibular molars was statistically significantly higher versus that of the other teeth groups. Eighteen of the patients did not consume any analgesic tablets, constituting 18.3% of the whole group. Two patients needed 5 tablets which was the greatest reported intake.Apicoectomy leads to low Ibuprofen intake. The sex is not a statistically significant factor for Ibuprofen use. Poor negative correlation is observed between age and the amount of administered analgesics. This consumption is increased at resection of mandibular molars compared to that for other teeth groups. Almost one fifth of the patients did not need analgesics during the first postoperative day.
- Effect of deep margin elevation on fracture resistance of premolars restored with ceramic onlay: in vitro comparative study(2023) Salah, Zahraa; Sleibi, AhmedThis in vitro comparative study aimed to compare the influence of two levels of deep margin elevation (2 and 3 mm) with either bulk-fill flowable composite or short fiber-reinforced flowable composite on the fracture resistance of maxillary first premolars restored with ceramic onlays.Fifty sound-extracted maxillary first premolar teeth were selected to prepare mesio-occluso-distal cavities with standardized dimensions. The cervical margins were extended 2 mm below the cemento-enamel junction on both mesial and distal sides. These teeth were randomly divided into five groups: Group I: no box elevation (control group). Group II: 2 mm marginal elevation with bulk-fill flowable composite. Group III: 2 mm marginal elevation with short fiber-reinforced flowable composite. Group IV: 3 mm marginal elevation with bulk-fill flowable composite. Group V: 3 mm marginal elevation with short fiber-reinforced flowable composite. After cementation, all teeth were subjected to a fracture resistance test using the universal testing machine, and the mode of failure was analyzed using a digital microscope at 20x magnification.The result showed a non-significant difference in the fracture resistance between 2 and 3 mm marginal elevation (p>0.05) with respect to each restorative material used for deep margin elevation. However, the fracture resistance of teeth elevated with short fiber-reinforced flowable composite was significantly higher than those elevated with bulk-fill flowable composite at both levels 2 and 3 mm, p=0.041 and 0.038 respectively.The fracture resistance of premolars restored with a ceramic onlay was not influenced by the levels of deep margin elevation (2 or 3 mm). However, marginal elevation with short fiber-reinforced flowable composites provided higher fracture resistance than those elevated with bulk-fill flowable composites, and those without marginal elevation.
