Log In 
Language Medicina oral, patología oral y cirugía bucal. Ed inglesa. 2008. Vol. 13, no. 11
Permanent URI for this collection
Browse
Recent Submissions
Now showing 1 - 15 of 15
- Microtensile bond strength of resin-post interfaces created with interpenetrating polymer network posts or cross-linked posts(2008) Mannocchi, Francesco; Machmouridou, Eleni; Watson, Timothy F.; Sauro, Salvatore; Sherriff, Martyn; Pilecki, Peter; Pitt Ford, T.R.Objective: The purpose of this study was to evaluate the microtensile strength of composite bonded to interpenetrating polymer network (IPN) or cross-linked glass fibre posts and to observe the failure modes by using light and scanning electron microscopy. Methods: Twenty posts containing IPN resin matrix and 20 posts containing cross-linked epoxy polymer matrix were used for testing. One half of the posts from each type was treated with Stick Resin, the other half was treated with OptiBond. Composite resin was used to build up a block on the bonding surface. Tensile strength data was analysed statistically using the non-parametric Kaplan-Meier survival analysis. The distribution of failure modes as a function of post type/bonding agent was evaluated using the ?² test. Results: The mean tensile strength values were lower for the groups bonded with OptiBond and higher for the groups bonded with Stick Resin (p = 0.017), the type of post used had no statistical significance (p = 0.263). All the IPN posts showed cohesive failure within the post The cross-linked posts demonstrated a higher number of adhesive failures and lower number of cohesive failures within the post (?² = 0.0001). Conclusions: Stick Resin was more effective than OptiBond in bonding composite cores to fibre posts. Post fracture was the failure mode of IPN posts, debonding of the composite core was the failure mode of most of cross-linked posts. These different failure modes may appear clinically in endodontically treated teeth restored with the post types tested in this study.
- Assessment of quality of life in oral cancer(2008) Torres Carranza, E.; Hernández Guisado, J. M.; Hens Aumente, Elena; Gutiérrez Pérez, José LuisQuality of life (QL) in oral cancer patients has become one of the most important parameters to consider in the diagnosis and post-treatment follow-up. The purpose of this article has been to review the papers published that study the QL in oral cancer patients, the different QL questionnaires used, the clinical results obtained, and the systematic revisions available in the indexed literature for the last 10 years. The term QL appears as a keyword in an increasing number of articles throughout the past 10 years; however, few studies focus on oral cancer. Most of them assess all head and neck cancers, which conform to a heterogeneous group with several different features depending on location (oral cavity, oropharynx, larynx, hypopharynx, nasopharynx and salivary glands). Most studies evaluate QL in short periods of time, normally within the first year after the diagnosis. Series do not discern between different therapeutic options, and they generally center on Northern European or Northern American populations. There are few instruments translated and validated into Spanish that measure QL, a fundamental characteristic to link QL to own patients? socio-cultural parameters. Data related with QL are mostly related to patient (age, sex, co-morbidity), tumour (location, size), and treatment (surgical treatment, radiotherapy association, reconstruction, cervical dissection, and/or feeding tube). Nowadays QL?s assessment is considered an essential component of an oral cancer patient as well as the survival, morbidity and years free of disease. Although many aspects related to QL in oral cancer patients have been published throughout the past 10 years, more systematic research is needed to be able to apply it on a daily basis.
- Inferior alveolar nerve transposition with involvement of the mental foramen for implant placement(2008) Vasconcelos, Juliano de Alencar; Bertozzi Ávila, Gisseli; Ribeiro, José Carlos; Dias, Sérgio Candido; Pereira, Luciano JoséInferior Alveolar Nerve (IAN) transposition is an option for prosthetic rehabilitation in cases of moderate or even severe bone reabsorption for patients that do not tolerate removable dentures. The aim of the present report is to describe an inferior alveolar nerve transposition with involvement of the mental foramen for implant placement. The surgical procedure was performed under local anesthesia, by the inferior alveolar, lingual and buccal nerve blocking technique. Centripetal osteotomy was performed, and bone tissue was removed, leaving the nerve tissue free in the foramen area. After that, transsection of the incisor nerve was performed, and lateral osteotomy was started from the buccal direction, toward the trajectory of the IAN. The procedure was concluded, by making use of a delicate resin spatula to manipulate the vascular-nervous bundle. The drilling sequence for placing the dental implants was performed, and autogenous bone was harvested using a bone collector attached to the surgical suction appliance. After the implants were placed, the bone tissue previously collected during the osteotomies and drilling processes was placed in order to protect the IAN from contact with the implants. The surgical protocol for inferior alveolar nerve transposition, followed by implant placement presented excellent results, with complete recovery of the sensitivity, seven months after the surgical procedure.
- Interactions between ibuprofen and antihypertensive drugs : Incidence and clinical relevance in dental practice(2008) Salort Llorca, Cesar; Mínguez Serra, María Paz; Silvestre Donat, Francisco JavierIt has been well documented in the literature that ibuprofen interacts with different groups of antihypertensive drugs (beta-adrenergic blockers, alpha-adrenergic blockers, diuretics and angiotensin-converting enzyme inhibitors), reducing their antihypertensive activity. The mechanism of action of ibuprofen involves inhibition of the enzyme cyclooxygenase, thereby inhibiting the synthesis of inflammatory prostaglandins and vasodilatory prostaglandins that increase renal blood flow and thus favor the excretion of water and sodium. More than five days of treatment with both drugs are normally required for the interaction to manifest. Although the changes in blood pressure resulting from this interaction are typically small, some patients can experience substantial elevations in both systolic and diastolic blood pressure. It has been estimated that the avoidance of minor changes in systolic pressure in patients with osteoarthritis subjected to treatment with nonsteroidal antiinflammatory drugs would avoid over 30,000 deaths due to myocardial infarction, and over 2000 deaths due to coronary disease, in the United States alone.
- Oral metastasis of renal cell carcinoma : presentation of a case(2008) Narea Matamala, Gonzalo; Fernández Toro, María de los Ángeles; Villalabeitía Ugarte, Elías; Landaeta Mendoza, Mirtha; Rojas Alcayaga, GonzaloThe oral cavity constitutes a site of low prevalence for metastasis of malignant tumors. Nevertheless, it has a high prevalence for metastasis of renal origin. Besides the kidneys, there are other primary sites with high prevalence of metastasis to the oral mucosa, such as the lungs, skin and breasts. Metastasis is common in patients with a background of treated renal tumors, thereby, it is proper to determine the possibility of oral metastasis as part of the protocol of attention. However, it constitutes a diagnostic challenge when it presents in patients with no renal antecedents. It is in this type of patients that the diagnosis of carcinoma is achieved by means of a metastasis. Survival rate in these patients is short because at the time of the metastasis diagnosis, the general compromise is high. The following report describes a case referred from the Rheumatology Unit with an intraoral tumor, that was finally diagnosed as a Metastasic Renal Cell Carcinoma with multiple metastasis.
- Metaanalysis of the epidemiology and clinical manifestations of odontomas(2008) Hidalgo Sánchez, Olga; Leco Berrocal, María Isabel; Martínez González, José MaríaObjective: To evaluate the epidemiological and clinical aspects of the different types of odontomas. Study design: A metaanalysis was made of 3065 odontomas obtained from a literature review of 30 articles published in recent years. Results: Odontomas show no gender predilection, and are most often diagnosed in the second decade of life. They are preferentially located in the upper maxilla, particularly in the anterior sector. Compound odontomas are more prevalent than complex odontoma, and show no predilection in terms of patient gender, age or location. Most such lesions are asymptomatic and constitute casual findings in X-ray studies indicated for other reasons. The most common clinical manifestations are the retention of permanent teeth and the presence of a tumor. Treatment consists of surgical removal of the lesion. The prognosis is very good, with a scant tendency towards relapse. Conclusions: Odontomas are the most common odontogenic tumors. Their most significant characteristics comprise alterations in tooth eruption, and the diagnosis is casually established in the course of routine X-ray studies.
- Pain and swelling in periapical surgery : a literature update(2008) García Mira, Berta; Larrazabal Morón, Carolina; Peñarrocha Diago, María; Peñarrocha Diago, MiguelIn recent years, periapical surgery (PS) has evolved thanks to the incorporation of technical and diagnostic advances. In PS, secondary effects such as pain and swelling occur as with all surgical procedures. The objective of the present study is to review the literature of articles published on pain and swelling during the postoperative period in periapical surgery. For this review, a search was made in Medline and of literature published in Spanish odontological journals. In the reviewed literature the maximum pain was produced during the first 24 postoperative hours and maximum swelling between the first and second day. Recent studies propose the use of corticoids and nonsteroidal anti-inflammatory drugs (NSAIDs) during the pre-and post-operative period, in order to reduce pain perception during the first postoperative week after surgery. Likewise, low-level laser therapy has been used; although with no statistically significant results being observed for the control of pain. In the majority of published studies there was no statistically significant relationship between age and sex and the postoperative symptoms. However, greater pain and swelling is observed in patients with poor oral hygiene before surgery, and higher pain in patients who smoke, and in those with pain before surgery. Surgery of anterior teeth and molars is associated with greater pain.
- Primary oral myiasis : a case report(2008) Sharma, Jyoti; Mamatha, G.P.; Acharya, RachanaMyiasis is the infestation of live human and vertebrate animal with dipterous larvae which feed on the host?s dead or living tissue. A case of oral myiasis in the maxillary anterior region in a 42-year-old female with neurologic deficit caused by the larvae (maggots) of Musca Nebulo (Family Diptera) is reported. The treatment consisted of manual removal of the larvae by topical application of turpentine oil, oral therapy with ivermectin and surgical debridement of the oral wound.
- Relationship between oral Kaposi ?s sarcoma and HAART : Contribution of two case reports(2008) Campo Trapero, Julián; Romero, Jorge del; Cano Sánchez, Jorge; Rodríguez Martín, Carmen; Martínez González, José María; Bascones Martínez, AntonioTwo HIV infected patients not receiving Highly Active Antiretroviral Treatment (HAART) presented with epidemic Kaposi?s sarcoma of the oral cavity. One patient initially refused HAART, but when the lesion became large enough to be noticeable he agreed to HAART associated with excision of the intraoral lesion by CO2 laser. The other patient developed KS and progressed to AIDS at two years after ceasing HAART due to adverse effects; he was referred to hospital for renewed administration of HAART. In both cases, the lesions observed in the oral cavity were the first clinical manifestation of AIDS. These reports underline the close relationship between the use of HAART and the control of KS lesions, highlighting the important role of the dentist in the identification and early diagnosis of these oral lesions.
- Prevalence of oral lesions in patients with psoriasis(2008) Hernández Pérez, Francisco; Jaimes Aveldañez, Alejandra; Urquizo Ruvalcaba, Ma. de Lourdes; Díaz Barcelot, Moises; Irigoyen Camacho, María Esther; Vega Memije, María Elisa; Mosqueda Taylor, AdalbertoAim: To determine the prevalence of oral lesions (OL) in patients with psoriasis, and compare these findings with the ones found in patients without this condition. Materials and methods: In the present observational and comparative study, we evaluated 207 patients, with and without psoriasis, attending the dermatological consulting service of a concentration hospital in Mexico City. The possible association between OL and psoriasis was analyzed through a logistic regression model; the Odds Ratio (OR) and its Confidence Interval (CI) was calculated to be 95%. Results: Two hundred and seven cases were examined (80 with psoriasis and 127 without psoriasis). Of these, 75 (36.2%) were men and 132 (63.7%) women. Oral lesions were found in 54 (67.5%) psoriatic patients and in 63 (49.6%) of the comparative group (p <0.012). Fissured tongue (FT) was present in 47.5 % of the patients with psoriasis and in 20.4 % of the group without psoriasis, (OR=3.46, 95% CI [1.14, 10.5], p=0.001). Geographic tongue (GT) was present in 12.5 % of the group with psoriasis and 4.7 % in the group without this disease (OR=3.54 95 % CI [1.97, 6.79], p=0.028). Likewise, six patients (7.5 %) with psoriasis and 3 (2.36 %) from the comparative group presented simultaneously GT and FT (p = 0.0776). The most frequent type of psoriasis was the vulgar psoriasis (90 %), in which a higher prevalence of FT (p <0.05) was present. There were no differences between both groups (p>0.05) regarding the use of tobacco. Alcohol consumption was greater (55.0%) among patients with psoriasis than among those without psoriasis (26.7%) (p<0.05), but when the association with GT and FT was analyzed, no significant differences were found among consumers and not consumers of tobacco and alcohol (p> 0.05). Conclusions: The high prevalence of GT and FT in patients with psoriasis suggests that these lesions should be taken into account in new studies as possible predictors or markers of the severity of this dermatosis, in order to confirm the association of these entities.
- Cell proliferation and apoptosis in keratocystic odontogenic tumors(2008) Mateus, Gláucia Cardoso Paixão; Lanza, Gleyson Henrique dos Santos Pena; Moura, Pedro Henrique Ribeiro de; Marigo, Helenice de Andrade; Horta, M.C.R.Objectives: Keratocystic odontogenic tumors (KOTs), also known as odontogenic keratocysts, were recently classified as a benign neoplasia due to the aggressive clinical behavior. Although several studies have shown the high proliferative activity of the epithelial lining, few studies have evaluated apoptosis in KOTs. Therefore, the aim of this study is to evaluate and compare the proliferation index (PI) and the apoptotic index (AI) of the epithelial lining in sporadic KOTs, KOTs associated with the Nevoid Basal Cell Carcinoma Syndrome (NBCCS KOTs), and dentigerous cysts. Material and methods: A total of 11 sporadic KOTs, 15 NBCCS KOTs, and 11 dentigerous cysts were evaluated. The PI was assessed by immunohistochemical detection of the cell proliferation marker Ki-67. The AI was assessed by morphological evaluation of sections stained by methyl green-pyronin. The TUNEL assay was used to confirm the occurrence of apoptosis. Differences in the PI and the AI between sporadic KOTs, NBCCS KOTs, and dentigerous cysts were analyzed using the Kruskal-Wallis test. Differences in the PI and the AI between the epithelial layers of each lesion were analyzed using the Wilcoxon test. Results: The PI and AI were higher in sporadic and NBCCS KOTs than in dentigerous cysts. No difference in these indexes was observed between sporadic and NBCCS KOTs. In dentigerous cysts, the PI was higher in the basal layer. In sporadic and NBCCS KOTs, the PI was higher in suprabasal layer. No difference in the AI was observed between the basal layer and the suprabasal layer in the three lesions. The AI was higher in the superficial layer of sporadic and NBCCS KOTs. Conclusions: The present study demonstrates that the epithelial lining of KOTs shows a distinct pattern of cell proliferation and apoptosis, reflecting its high cell turnover and reinforcing its classification as an odontogenic tumor.
- Qualitative and quantitative exfoliative cytology of normal oral mucosa in type 2 diabetic patients(2008) Shareef, Ban Tawfeek; Ang, Kok Teong; Naik, Venkatesh RamasamyObjective: The main purpose of this study is to emphasize the relevance of exfoliative cytology as an additional tool to aid in the diagnosis of diabetes mellitus. Materials and Methods: This is a comparative cross-sectional study. Oral smears were obtained from 10 diabetic patients and 10 healthy individuals. These smears were stained with Papanicolaou stain. The nuclear (NA) and cytoplasmic (CA) areas of 20 integral cells predominant in the buccal mucosa were measured using the Leica Qwin Version 2.1 image analysis system (LEICA GMBH GERMANY).The cytoplasmic/nuclear ratio (C/N) was then calculated. For comparing cytomorphometric parameters (NA, CA and C/N ratio) the Mann-Whitney test was used. Significance was set at P ? 0.05. Results: The morphologic alterations seen in buccal mucosal epithelial cells of the diabetic group were nuclear enlargement, karyorrhexis, binucleation and infiltration of polymorphonuclear leukocytes. The NA was significantly higher (P < 0.05) in the diabetic group. The CA between these two groups were not significantly different (P > 0.05). The C/N mean was significantly lower (P < 0.05) in the diabetic group. Conclusion: Exfoliative cytology is useful as an additional tool to aid in the diagnosis of diabetes mellitus
- Prevalence of leukoplakia, oral submucous fibrosis, papilloma and its relation with stress among green marbles mine laborers, India(2008) Dagli, Rushabh J.; Kumar, Santhosh; Mathur, Anmol; Balasubrimanyam, Gautham; Duraiswamy, Prabu; Kulkarni, SuhasObjectives: To determine the prevalence of leukoplakia, oral submucous fibrosis and papilloma among ?Green Marble Mines? laborer and uncover its relation with occupational stress. Methods: Mines were divided in four geographic zones, and participants were selected by stratified cluster sampling technique. A total of 513 subjects were included in final study which were alienated among the four age cohort 15-24 , 25-34 , 35-44, 45-54 respectively. The study was been conducted following the research methodology recommended by World Health Organization- Oral Health Surveys 1997. A questionnaire from ?Union of Shops, Distribution and Allied Worker (USDAW) Nationwide, Manchester? was used for stress assessment of mine workers and clinical examination for oral mucosa was conducted by one of the three examiner with the aid of an artificial light source. The kappa statistics for diagnosis of leukoplakia, oral submucous fibrosis and papilloma was determined (field teams versus expert) 0.81, 0.92 and 0.89 respectively two days prior to the examination. Data was analyzed using bivariate and multivariate analysis. Results: An overall elevated prevalence of all three oral-mucosal lesion was found among mine workers (36.7%), mainly leukoplakia affecting 171 mine workers (33.3%). The affected workers were having body problems like headache, backache and stressed due to under-payment. Individuals having papilloma have faced problem at work like noise, dust or fumes and poor maintenance of equipment. Multiple logistic regression analysis model of oral-mucosal lesion have shown highly significant relation (p<0.01) with increased stress, age, alcohol habits and malnutrition. Conclusion: The prevalence of oral mucosal lesion is higher, among marble mine laborers, and occupational stress can intensify the disease condition. Curative services along with prevention and stress reduction program, requires primary anticipation.
- Progressive rise of c fos expression from premalignant to malignant lesions of oral cavity(2008) Sachdev, Ritesh; Mandal, Ashish Kumar; Singh, Ishwar; Agarwal, Arun KumarObjectives: Oral cancer is a worldwide phenomenon. It is thought to develop in a number of premalignant lesions. Protooncogene c fos is a known transformer of premalignant to malignant lesions. However, its role in oral carcinogenesis is not yet known. Study design: A total of 130 cases were studied comprising of premalignant lesions (n=50), squamous cell carcinoma (n=50) and controls (n=30). c fos expression was studied by immunohistochemistry. Results: Premalignant lesions of oral cavity occurred at a lower age group (mean 39.2 years) compared to squamous cell carcinoma (mean 51.8 years), p <0.001. Mean c fos percentage positivity in squamous cell carcinomas (SCC), premalignant lesions and controls was 44.5±36.9%, 11.4±18.8% and 1.23±2.6% respectively, the differences were highly significant (p<0.001). c fos positivity also increased from mild (10.85±14.23%) to moderate dysplasia (19.64 ±26.05%). Conclusions: The serially increasing c fos expression from normal mucosa to premalignant lesions to SCC and in dysplasias suggests that it could be an early gene to get activated and form transcription factor activator protein ?1(AP-1).
