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Language Journal of Clinical and Experimental Dentistry. 2025. Vol. 17, no. 07
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- Management of external root resorption following replantation after accidental tooth extraction using regenerative endodontic procedures: a case report(Medicina Oral S.L., 2025) Le, Hong Van; Vu, Thai Son; Nguyen, Ngoc Linh Chi; Le, Kim NhaAccidental extraction of the wrong tooth can lead to complications such as external root resorption (ERR) after replantation. This case report describes the management of an 11-year-old female patient with ERR in a replanted mandibular first molar (#36) following iatrogenic extraction. Regenerative endodontic procedures (REPs) were employed, including chemical disinfection, intracanal calcium hydroxide medication, blood clot induction, and the placement of Biodentine™. Follow-up over 24 months showed resolution of clinical symptoms, arrest of root resorption, healing of periapical lesions, and complete apical closure. Cold pulp testing yielded positive results after 12 months, confirming regenerative response. This case highlights the potential of REPs as a biologically based approach for managing complex endodontic conditions involving root resorption, even in mature permanent teeth. It contributes to the growing body of evidence supporting REPs as a viable option in the treatment of tooth avulsion.
- Management of a Periodontally Hopeless Tooth with Intentional Re-implantation(Medicina Oral S.L., 2025) Konduri, Divya; Gooty, Jagadish Reddy; Guntakandla, Vikram Reddy; Reddy, S. Jaya Prada; Palaparthy, Raja Babu; Josephin, JulietIntentional replantation is a process that involves purposeful tooth extraction and subsequent reinsertion of the removed tooth. Intentional replantation may be a therapeutic option worth considering to preserve the natural teeth and prevent tooth extraction, even though the success rate is not always high. Systemically healthy male patient was referred to our department. Diagnosis was chronic periodontitis and class III mobility was noted at the right maxillary central incisor with complete periodontal attachment loss. After phase I therapy periodontally involved tooth was extracted, endodontic treatment was accomplished, the tooth was replanted and stabilized with a composite wire splint. At the end of 3 years tooth was in function with alveolar bone gain. Intentional replantation provided long-term maintenance of patient’s own teeth and can be considered as an alternative treatment option tooth with hopeless prognosis.
- “The Safety Check”: a simple and reproducible intraoperative test to support surgeons in training during ALT flap harvesting(Medicina Oral S.L., 2025) Aragón Niño, Íñigo; Ma, Hailong; He, YueThe anterolateral thigh (ALT) flap is widely used in reconstructive surgery due to its versatility and favorable donor site characteristics. However, its harvest remains technically challenging, primarily due to the anatomical variability of the perforators. Experienced surgeons make intraoperative decisions based on anatomical knowledge, tactile feedback, and visual cues, but these skills may be underdeveloped in surgeons in training, increasing the risk of complications. To address this issue, we present “The Safety Check,” a simple and reproducible intraoperative test designed to assist trainees in decision-making during ALT flap harvest. This method is based on the visual assessment of arterial pulsatility along the course of perforators and the pedicle, formalizing a step that is often intuitive for experienced surgeons. The technique was applied in 52 cases over a 6-month period, with perforators monitored in three phases: before dissection, during dissection, and after dissection until flap elevation. Preliminary results showed that “The Safety Check” improved trainee confidence, facilitated the early identification of compromised perforators, and increased surgical efficiency without adding significant time to the procedure. Additionally, the method served as an educational tool, fostering active learning and intraoperative discussions. While no quantitative data were collected, qualitative feedback supported its value as an adjunct to training in perforator flap techniques.
- Clinical manifestations in the maxillofacial region of acute crisis of sickle cell anemia:: a case report(Medicina Oral S.L., 2025) Andura-Correas, Martín; Chacón-Ferrer, Guillermo; Vázquez-Salgueiro, Eduardo; Ortiz Peces, Luis; Moreiras Sánchez, Álvaro Damián; Noguera Tomás, Jorge; Cebrián Carretero, José LuisSickle cell anemia, or sickle cell disease, is a hematologic condition commonly found in populations from the Middle East, India, the Caribbean, and the Mediterranean. One of its complications is the development of long bone osteomyelitis. However, mandibular bone involvement is rare, which makes early diagnosis of this disease difficult when it affects this anatomical region. In this article, we present the case of a 25-year-old male with a prior diagnosis of sickle cell anemia who developed mandibular osteomyelitis associated with a paramandibular abscess and ipsilateral temporomandibular joint involvement, which was diagnosed and treated medically and surgically. Through this case, we aim to provide clinical insight into mandibular infectious complications associated with sickle cell anemia, along with their diagnosis and therapeutic management. Multidisciplinary care, clinical evaluation, laboratory findings, and imaging studies are the main pillars for the management of this disease. Furthermore, we review the literature on the clinical presentation, diagnosis, and treatment of mandibular osteomyelitis in patients with sickle cell disease.
- Microfiltration of glass ionomer restorations in teeth treated with silver diamine fluoride: a scoping review(Medicina Oral S.L., 2025) Avellaneda Gonzales, Ana Lucia; Cruz Flores, Maria Elizabeth; Roncal Espinoza, Rosa; Rendón Alvarado, AlfredoBackground: The current approach to dental caries focuses on early diagnosis and intervention at initial stages. In the presence of a carious lesion, a minimally invasive strategy is favored. Within this context, materials have been developed to promote remineralization, prevention, and conservative treatments, with silver diamine fluoride (SDF) standing out as an effective alternative. The purpose of this scoping review is to evaluate, through a literature review, the success of restorations in teeth treated with SDF, using microleakage as the evaluation parameter. Material and Methods: A search was conducted in electronic databases including PubMed, Virtual Health Library, EBSCOHost, SCOPUS, ProQuest, and ScienceDirect. The search was carried out up to May 24, 2024, following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Results: A total of 298 articles were retrieved, of which only 8 met the inclusion criteria and were used for the literature review. The selected studies underwent a quality control review to assess the success of restorations in teeth treated with SDF. Conclusions: Although information on the effect of SDF on the adhesion of resin-modified glass ionomer restorations is limited, some studies show no correlation indicating that prior SDF treatment causes microleakage in such restorations.
- Strengthening Collaborations in Latin America for Advancing Oral cancer research and public health policies(Medicina Oral S.L., 2025) Schussel, Juliana Lucena; Villarroel Dorrego, Mariana; Niklander, SvenBackground: Oral cancer (OC) represents a significant public health challenge in Latin America, with similar challenges presented in most countries of the region. Regional partnerships are needed, as they can enhance the development of educational campaigns, prevention strategies addressing shared risk factors, and institutional strengthening. Additionally, expanding collaborations can attract international funding and integrate LAC researchers into global initiatives.Material and Methods: This review examines the state of OC research in the region, highlighting collaborative efforts, gaps, and opportunities for advancement.Results: We identified 17 studies that have studied different aspects of oral cancer in Latin American countries (LAC). Studies varied in design, with ecological studies and case series being the most common. Most studies focused purely on OC, while research on oral potentially malignant disorders (OPMD) remains limited. Collaborative studies have increased over the past decade, with a growing focus on regional risk factors such as tobacco and alcohol use. Despite these advances, challenges persist, including limited epidemiological data, underreporting of cases, and inadequate public health infrastructure.Conclusions: Collaborative networks have the potential to reduce these gaps by pooling resources, expertise, and data. Improved public health policies supported by robust local data are crucial for reducing the OC burden in LAC.Strengthening regional and international collaborations will be fundamental for the advancement of OC research, improving early detection, and implementing effective prevention and treatment strategies tailored to the region’s unique challenges.
- Clinical assessment of marginal and bulk fractures and discoloration in posterior composite after 12 to 36 months: a retrospective study(Medicina Oral S.L., 2025) Motamedosanaye, Vahideh; Akbari, Hadi; Ziaaddini, Sara; Mostafazadehbakhtiyary, Mohammad; Sadat Langari, AtefehBackground: This retrospective cohort study aimed to evaluate the marginal discoloration, fractures, and bulk fractures of posterior composite restorations over a period of 1 to 3 years. Material and Methods: A total of 281 restorations, performed by a restorative dental specialist, were assessed using modified United States Public Health Service (USPHS) criteria. Demographic data, occlusal information, and patient habits were collected, along with characteristics of the restoration (composite resin type, adhesive, restoration type, and treated tooth). Data were analyzed using the chi-square test and independent t-test (α = 0.05). Results: Posterior Gradia, P60, and X-tra Fil were employed in 51.2%, 38.07%, and 14.23% of the restorations, respectively. Most of the restorations (81.5%) received an Alpha score for marginal discoloration, which was signif icantly associated with composite resin type, colored beverage consumption, oral hygiene, caries risk, and restoration classification (P < 0.05). Bravo discoloration was more common in patients who received Xtra Fil composite, consumed moderate to high amounts of colored beverages, had moderate to poor oral hygiene, and exhibited high caries risk. Additionally, Bravo discoloration was more frequent in Class II and build-up restorations. Restorations with a Bravo score were found to have significantly higher average restoration age, patient age, and a greater number of missing teeth compared to those with an Alpha score (P < 0.05). In terms of marginal fractures, 99.6% of restorations received an Alpha score, with no significant associations with the evaluated variables. Furthermore, 99.6% of restorations showed no bulk fractures. Conclusions: Posterior composite resin restorations demonstrated clinically acceptable performance with respect to marginal discoloration and integrity after 12 to 36 months.; Composite filling, marginal fracture, bulk fracture, discoloration.
- Blood pressure measurement in dental offices and dentists’ cardiovascular risk management: a cross-sectional study(Medicina Oral S.L., 2025) Otero, Johanna; Guerrero-Martín, Mario; Ortiz, YamilethBackground: Blood pressure measurement (BPM) is a primary test for detecting and managing cardiovascular risk, is an inexpensive strategy and can be performed by non-physician health workers (NPHWs). This study explored the association between the BPM in dental offices and other dentists’ practices related to cardiovascular risk management. Material and Methods: A cross-sectional study was conducted. A self-administered electronic survey was used, validated by experts with more than 10 years of clinical, teaching and research experience. Simple random sampling was used to select the participants at an anonymized database. The survey was completed by dentists who practice clinically at least part-time in Colombia. Descriptive and multivariate analyses were conducted. Results: A total of 232 dentists were interviewed. Blood pressure was measured in the dental office by 40.5% of the dentists, with 27.2% using an automatic device. After adjusting for age, education, and support staff, an association was observed between the absence of BPM in dental offices and the following practices: not inquiring about alcohol use, physical inactivity, high cholesterol, obesity, a lower likelihood of measuring glucose in the dental office, not referring patients to a laboratory for glucose measurement, not communicating with medical professionals to arrange patient treatment, and not educating people with obesity about the risk of systemic disease. Conclusions: BPM in dental offices is limited. Most dentists report inquiring about modifiable cardiovascular risk factors, as well as making referrals, providing counseling, and offering education. However, the absence of BPM in dental offices is associated with the omission of other practices related to cardiovascular risk management. NPHWs like dentists can task sharing cardiovascular risk management.
- Concordance between clinical and histopathological diagnoses of oral and maxillofacial lesions in thailand:: a 20-year retrospective study(Medicina Oral S.L., 2025) Teerawong, Chanyanuch; Chulaksanadecha, Tanyaaonann; Anansila, Thiyada; Krasaetanont, Punnapa; Intapa, Chaidan; Chompunud Na Ayudhya, ChalatipBackground: Accurate diagnosis is crucial for effective treatment planning and management. This study aims to evaluate the concordance between clinical and histopathological diagnoses of oral biopsy specimens submitted to the Oral Pathology Unit, Faculty of Dentistry, Naresuan University, Thailand, over a 20-year period. Material and Methods: Histopathology reports from 2004 to 2023 were retrieved and reviewed. Data on age, gender, lesion location, clinical diagnosis, and histopathological diagnosis were collected. The concordance between clinical and histopathological diagnoses, as well as factors associated with the concordance rate, were analyzed. Results: Of 1,253 biopsied cases, a total of 1,148 were included in the study. These comprised 513 males (44.69%) and 635 females (55.31%), with an average age of 40.97 ± 20.70 years. The majority of lesions were reactive and inflammatory lesions (35.1%), followed by epithelial pathology (10.02%), and immune-mediated lesions (7.58%), respectively. Twenty-nine cases (2.53%) were malignant. Overall, clinico-pathological concordance was observed in 69.34% of cases. The highest and lowest concordance rates were noted in immune-mediated lesions and non-odontogenic cysts and tumors, respectively. Conclusions: There is considerable variability in concordance among different oral lesion types. The results of this study provide insights into the prevalence of oral lesions in a group of Thai population and offer a valuable database for clinicians in developing clinical diagnoses for oral lesions.
- Surface microhardness and depth of cure in bulk fill resin composites with and without preheating: an in vitro study(Medicina Oral S.L., 2025) Pérez Pachas, Brisseth; Shibuya Panduro, Fiorella; Castro-Ramírez, Leonor; Cervantes Ganoza, Luis; Ladera Castañeda, Marysela Irene; Huamani-Echaccaya, José-Luis; Cayo Rojas, César FélixBackground: Preheating bulk-fill resins reduces their viscosity, facilitates their adaptation, and improves polymerization by accelerating the activity of photoinitiators. This would allow for more efficient application and deeper curing. The study’s objective was to compare the surface microhardness and depth of cure of three bulk-fill composite resins with and without preheating. Material and Methods: Sixty samples were prepared from three different materials, Aura Bulk Fill, Filtek One Bulk Fill, and Opus Bulk Fill, in standardized molds. A Vickers electronic hardness tester was used to measure the surface microhardness. The depth of cure was calculated using the upper-to-lower microhardness ratio for each sample. Robust Student’s T was used to compare two independent measures, and Welch’s robust ANOVA was used to compare more than two independent measures with Games Howell’s post hoc. Significance was set at p0.05). Conclusions: Preheating significantly increased the surface microhardness in Aura Bulk Fill and Filtek One Bulk Fill resin, while it caused the opposite effect in Opus Bulk Fill resin. In addition, preheating did not increase the depth of cure of each Bulk Fill resin evaluated. Finally, with and without preheating, Filtek One Bulk Fill resin presented higher surface microhardness and depth of cure than Aura Bulk Fill and Opus Bulk Fill resins.
- Association of hyperdivergent facial pattern and the inclination of the occlusal plane in orthodontic patients: across-sectional study(Medicina Oral S.L., 2025) Sánchez-Tito, Marco; Melgar Gutiérrez, Jorge; Cabrera Matta, AilinBackground: To evaluate the association between the hyperdivergent facial pattern and occlusal plane inclination in patients undergoing orthodontic treatment. Material and Methods: A retrospective cross-sectional study was conducted using records from patients who attended an orthodontic consultation at a specialized clinic in Tacna, Peru, between July 1, 2022, and August 31, 2023. Occlusal plane inclination was measured on lateral cephalometric radiographs following Andrews’ guidelines. Cephalometric analysis was performed using the OneCeph application. The vertical facial pattern was determined by the Frankfurt-Mandibular Plane Angle (FMA). A multiple linear regression analysis with robust variance was used to assess associations, considering p-values < 0.05 as statistically significant. Results: Occlusal plane inclination was significantly associated with vertical facial pattern (p < 0.001), with hyperdivergent individuals showing the greatest inclination. Additional significant correlations were observed with facial angle, convexity angle (p < 0.001), lower anterior facial height (p = 0.012), overjet (p = 0.042), and skeletal relationship (p = 0.013). Multiple regression confirmed greater occlusal plane inclination in hyperdivergent individuals compared to normodivergent (β = 2.15°, p < 0.001) and hypodivergent (β = 2.75°, p < 0.001) patterns. Conclusions: The hyperdivergent facial pattern was significantly associated with increased occlusal plane inclination, underscoring the importance of considering vertical growth patterns during orthodontic diagnosis and treatment planning
- Evaluation of microleakage and micromorphological analysis of different self-adhesive restorative systems in class v cavities:: laboratory study(Medicina Oral S.L., 2025) Hamouda, Mohamed E.; Harp, Youniss S.; ElEmbaby, AbeerBackground: Microleakage is a common problem that affects the longevity of restorative materials in Class V cavities. It is influenced by factors such as the type of restorative materials, composition of the cavity margins and aging. This study aimed to evaluate and compare microleakage and micromorphological analysis of restoration-dentin interface for Class V cavities restored with resin modified glass ionomer cement, self-adhesive flowable composite and self-adhesive composite hybrid before and after thermocycling for 10000 cycles. Material and Methods: One hundred two sound premolars received standardized Class V cavities on their buccal surfaces with the gingival margin placed 1mm above the cementum-enamel junction. The prepared premolars were randomly divided into three groups according to the self-adhesive restorative systems used (n=34). Each group was further subdivided into two subgroups according to aging (n=17); the first one was immediately evaluated after 24 hours of restoration placement, while the second was evaluated after thermocycling. Restored premolars were evaluated using dye penetration microleakage test under a stereomicroscope and micromorphological analysis of restorations/dentin interface. Microleakage scores were statistically analyzed using Kruskal-Wallis test, Mann-Whitney U test and Wilcoxon Signed Rank test. Results: There was a statistically significant difference regarding microleakage between the used self-adhesive restorative systems (p<0.05). Self-adhesive composite hybrid had the highest microleakage scores followed by self-adhesive flowable composite while resin modified glass ionomer cement had the lowest microleakage scores. Also, there was a significant increase in the microleakage scores for the used restorative systems after thermocycling (p<0.05). Conclusions: Resin modified glass ionomer cement remains the material of choice for Class V cavities in the term of microleakage compared to self-adhesive flowable composite and self-adhesive composite hybrid. The sealing stability of the used self-adhesive restorative systems still questionable over time.
- Evaluation of the effect of gallic acid dentin treatment on the shear bond strength of the composite resin by using universal adhesive, in self-etch and total-etch strategies(Medicina Oral S.L., 2025) Ghanbarian, Saeedreza; Sharafeddin, Farahnaz; Farhadpour, HajarBackground: Gallic acid (GA), as a material with potentially beneficial effects in dentistry, was used in this study to investigate whether it affects the shear bond strength of composite to the dentin via self-etch and total-etch strategies of a universal adhesive. Material and Methods: Sixty intact molars with sectioned flat occlusal surfaces were treated with 1 wt.% and 2 wt.% GA solution before applying the universal adhesive in self-etch and total-etch modes. They were randomly divided into six groups (n=10): 1) self-etch control, 2) total-etch control, 3) 1% GA + self-etch, 4) 2% GA + selfetch, 5) 1% GA + total-etch, and 6) 2% GA + total-etch. Teflon molds were fixed on the prepared dentin surface, and then the composite was inserted into the molds and light cured. After spending 24 hours in a storage condition with 100% humidity at room temperature, specimens underwent the SBS test. The SBS values calculated by the universal testing machine were analyzed using ANOVA and Tukey’s post hoc tests (p < 0.05). Results: The application of 1% and 2% GA before using the universal adhesive revealed a significant increase in the mean SBS values compared to respective control groups (p < 0.001, p < 0.001), and the mean values for 1% GA were significantly higher than 2% GA in both etching strategies (p < 0.001, p < 0.001). The groups that utilized the universal adhesive with the total-etch method exhibited statistically higher SBS values than those using the selfetch approach, irrespective of applying GA and its concentration (p < 0.001). Conclusions: Applying 1% and 2% GA improved the shear bond strength of composite resin to the dentin in both self-etch and total-etch approaches with the universal adhesive. These findings indicate that GA holds great potential for expanded clinical applications.
- Positional changes of the maxillary permanent canines after treatment with facemask and hyrax: a retrospective cohort study(Medicina Oral S.L., 2025) Saldarriaga Valencia, Jenny Angélica; Santamaría vélez, Adriana; Alvarez Varela, Emery; Villegas, Luisa Fernanda; Jiménez, Iván; Manrique Hernández, Rubén Darío; Ardila Medina, Carlos Martín; Santos Pinto, AryBackground: Early treatment of Class III malocclusion in growing patients remains a significant orthodontic challenge due to unfavorable growth patterns. This study evaluates the positional changes of the maxillary permanent canines (Mx3) and the first maxillary permanent molars (Mx6) after early treatment of Class III malocclusion with maxillary expansion and protraction (MEP). Material and Methods: A retrospective cohort study was conducted, including a longitudinal and panoramic radiographic (panorex) analysis. Forty-one Class III patients with maxillary hypoplasia (25 females, 16 males) treated in mixed dentition with MEP were compared to an untreated control group of 41 patients (23 females, 18 males). Positional changes of Mx3 were assessed using panorex. Angulation and sectional location of Mx3 were classified according to Power & Short (PS), the Lindauer modification of Ericson & Kurol (L), and Warford (W). Results: No statistically significant differences were found in the PS and W analyses or in the height of Mx3 between the initial and final evaluations. The L analysis indicated that most Mx3 were located in sectors I and II. Some Mx3 in sector II progressed toward sector I. No Mx3 in the treated group had a poor prognosis, compared to only 3.7% in the control group. Most Mx3 maintained their L prognosis, with improvement observed in 22% of the control group and 29.3% of the treated group. The majority of Mx3 in the final evaluation had a favorable prognosis. Conclusions: The results indicate that MEP treatment does not cause unfavorable positional changes in Mx3 or Mx6 in these patients.
- Dimensional stability of pet-g clear aligners with different thickness through cyclic compressive load tests: an in vitro study(Medicina Oral S.L., 2025) Lorusso, Mauro; Tepedino, Michele; Rendina, Gianluca; Cazzolla, Angela-Pia; Esperouz, Fariba; Lo Russo, Lucio; Ciavarella, DomenicoBackground: The purpose of this in vitro study was to evaluate the dimensional stability of PET-G clear aligners. Material and Methods: Two starting passive aligners of different thicknesses (0.75 mm and 0.88 mm) were subjected to cyclic compressive loading tests using the Instron 3343 testing machine in the laboratory, both with and without saliva. The intermolar and intercanine distances, measured in the occlusal direction, and the intermolar and intercanine Facial Axis (FA) distances, calculated between the most vestibular points of the crowns defined as Facial Axis points, were recorded using the dedicated software 3Shape Orthoviewer. Finally, the aligners were scanned using a laboratory scanner (3Shape TRIOS®) and then compared with the untested aligners of the control group. Results: The 0.75-mm-thick aligners exhibited greater dimensional stability than the 0.88-mm-thick aligners when measuring intercanine distance, both with and without saliva. In contrast, the 0.88-mm-thick aligners demonstrated greater stability than the 0.75-mm-thick aligners when measuring intermolar distance under the same conditions. In the measurement of FA distances, higher values were observed at the molar level when the tests were conducted both with and without saliva, whereas no significant changes were observed in the intercanine distance. Conclusions: The 0.88-mm-thick aligners demonstrated better dimensional stability during tests with and without saliva in the intermolar distance, while the 0.75-mm-thick aligners showed better dimensional stability in the intercanine distance.
- Effect of EDTA and silane on the bond strength of cementing agents of glass fiber posts to root dentin(Medicina Oral S.L., 2025) Campelo, Renata de Freitas; da Silva Filho, José Evando; Caracas de Araújo, Ana Paula; Goes, Mario Fernando de; Sabóia, Vicente de Paulo Aragão; Novais, Polyanna Maria Rocha; Gurgel Filho, Eduardo DiogoBackground: This study aimed to evaluate the effect of dentin pre-treatment with EDTA and silanization of glass f iber posts on the bond strength of different resin cements to root dentin. Material and Methods: Fifty-six extracted single-rooted human teeth received endodontic treatment and were restored with White Post DC (FGM) 0.5 fiber posts. Samples were divided into four groups: (1) Relyx U200 without EDTA, (2) Relyx U200 with EDTA, (3) Relyx ARC without EDTA, and (4) Relyx ARC with EDTA. Each group had a silane-treated subgroup (n=7). Root canals were prepared with Peeso reamer No. 3, leaving 4 mm of filling. Posts were cleaned with absolute alcohol (1 min) and air-dried (30 s). Silane was applied to half the posts for 60 s, then air-dried for 30 s. Specimens were mounted on acrylic plates with low-melting adhesive and sectioned using an Isomet saw (200 rpm, constant irrigation) and extra-fine diamond disc. Three slices (~1.5 mm thick) were obtained per tooth (coronal, middle, apical thirds). Thickness was measured with a digital caliper. Slices were positioned cervical side down in a 3.5 mm support matrix. A force was applied at 0.5 mm/min using a rod with a 0.8 mm extra-fine tip. Data were analyzed using Kolmogorov-Smirnov and Student’s t-tests. Results: Relyx ARC showed higher bond strength than Relyx U200, regardless of silane or EDTA use. The combination of silane and EDTA did not significantly affect results (Relyx U200 p=0.402; Relyx ARC p=0.510). Adhesive failure at the cement/dentin interface occurred in 51.61% of all samples, regardless of technique. Conclusions: EDTA and/or silane did not influence the bond strength of fiber posts to root dentin.
- Influence of different size of prophylaxis brush on marginal microleakage and hybrid layer morphology of composite restorations(Medicina Oral S.L., 2025) Da Silva, Monique Evelin Pereira; Mendes, Maria Eduarda Da Silva; da Silva, Tayná Souza Gomes; Sobral-Souza, Danielle-Ferreira; Dias, Marlon-Ferreira; Lins-Filho, Paulo-Cardoso; Teixeira, Hilcia Mezzalira; de Andrade, Audrey Nunes; Neto, Antonio José Torres; Guimarães, Renata-PedrosaBackground: Tooth cavity cleaning is a fundamental step to achieve greater adhesion in composite resins restorations. This study aimed to evaluate the influence of different sizes of prophylaxis brush on marginal microleakage and hybrid layer morphology in composite restorations. Material and Methods: Thirty Class V tooth preparations were distributed into 3 groups according to the type of cavity cleaning (n=10): G1: no prophylaxis; G2: Prophylaxis brush with regular size (Robson Brush Prophylaxis/ DHPro); G3: Prophylaxis brush with reduced size (Robson Microtuft®/DHPro brush). After the respective cleaning protocol, third human molars were restored using a universal adhesive system (Single Bond Universal - 3M ESPE) and composite resin (FiltekTM Z350 XT 3M ESPE). To characterize the dentin substrate, the samples were prepared until the selective conditioning step and evaluated by scanning electron microscope (SEM) and hybrid layer’s morphology was also evaluated after the restorative procedure (n=2). To assess the marginal microleakage, the sample were submitted to the thermocycling process, finished, and polished. After this step, the images were obtained by Micro-CT, and two calibrated evaluators scored the depth of dye penetration as 0 to 3. The Kruskal-Wallis test was used to compare groups regarding marginal microleakage (p0.05).Conclusions: Therefore, the Robson Microtuft® brush did not influence the marginal infiltration of the adhesive restorations, but the absence of prior prophylaxis increased the levels of infiltration and obtained a more irregular adhesive interface.
- Surgery with leukocyte and platelet-rich fibrin (L-PRF) vs. surgery alone for medication-related osteonecrosis of the jaw: a randomized controlled trial(Medicina Oral S.L., 2025) Ramos, Emilio A.; Muiño, Juan M.; Diamante, Maximiliano; Echagüe, Alejo; Puia, Sebastian-Ariel; Caruso, DiegoBackground: Multiple studies have reported high resolution rates of medication-related osteonecrosis of the jaw (MRONJ) with surgical treatment combined with platelet concentrates. However, no randomized controlled trials have been published to date comparing surgery combined with L-PRF to surgery alone.Material and Methods: We conducted a multicenter, open-label, parallel-group, randomized controlled trial to assess the effect of leukocyte- and platelet-rich fibrin (L-PRF) as an adjunct to surgery for the treatment MRONJ.Patients were randomly assigned to either surgery combined with L-PRF or surgery alone. The primary outcome was the proportion of patients achieving complete resolution of MRONJ lesions six months postoperatively. Complete resolution rates were compared using the chi-square (X²) test, and relative risk (RR) with 95% confidence intervals (CI) was calculated. Secondarily, we evaluated baseline quality of life using the EQ-5D-3L questionnaire and assessed the impact of L-PRF on quality-of-life measures.Results: A total of 41 participants were included in the study. Nineteen participants underwent surgery with L-PRF, while 22 underwent surgery alone. At the six-month follow-up, complete resolution was observed in 92% (11/12) of patients in the experimental group and 83% (15/18) in the control group (RR 1.1, 95% CI 0.84–1.43, p=0.51).The most affected domains in the baseline quality-of-life assessment were anxiety/depression and pain/discomfort.No statistically significant differences were observed between groups in any quality-of-life domain at six months.Conclusions: Our findings suggest that the use of L-PRF as an adjunct to surgery does not provide a significant clinical benefit compared to surgery alone.
