Upconversion nanohybrids for NIR-induced photorepair of DNA etheno adducts
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Here, we report NIR-triggered photorepair of DNA damages via photosensitization by using well-known upconversion nanohybrids consisting of ytterbium and erbium co-doped core-shell upconversion nanoparticles (UCs) and Rose Bengal (UC@RB). Specifically, two purine-derived etheno adducts (1,N6-etheno-2'-deoxyadenosine (εdA) and 1,N2-etheno-2'-deoxyguanosine (εdG)) have been used as proof of concept.
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