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Recent Advances on the Halo- and Cyano-Trifluoromethylation of Alkenes and Alkynes
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Recent Advances on the Halo- and Cyano-Trifluoromethylation of Alkenes and Alkynes
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| Fu, Bo; Escorihuela Fuentes, Jorge; Han, Jianlin; Fustero Lardiés, Santos; Barrio Fernández, Pablo; Sodeoka, Mikiko; Kawamura, Shintaro; Sorochinsky, Alexander; Soloshonok, Vadim A. | |||
| This document is a artículoDate2021 | |||
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| Incorporation of fluorine into organic molecules is a well-established strategy in the design of advanced materials, agrochemicals, and pharmaceuticals. Among numerous modern synthetic approaches, functionalization of unsaturated bonds with simultaneous addition of trifluoromethyl group along with other substituents is currently one of the most attractive methods undergoing wide-ranging development. In this review article, we discuss the most significant contributions made in this area during the last decade (2012−2021). The reactions reviewed in this work include chloro-, bromo-, iodo-, fluoro- and cyano-trifluoromethylation of alkenes and alkynes. | |||
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Fu, Bo Escorihuela Fuentes, Jorge Han, Jianlin Fustero Lardiés, Santos Barrio Fernández, Pablo Sodeoka, Mikiko Kawamura, Shintaro Sorochinsky, Alexander Soloshonok, Vadim A. 2021 Recent Advances on the Halo- and Cyano-Trifluoromethylation of Alkenes and Alkynes Molecules 26 23 7221 |
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| https://doi.org/10.3390/molecules26237221 |
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23 - Química [991]