Does chlorhexidine improve outcomes in non-surgical management of peri-implant mucositis or peri-implantitis? : a systematic review and meta-analysis
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Does chlorhexidine improve outcomes in non-surgical management of peri-implant mucositis or peri-implantitis? : a systematic review and meta-analysis

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Does chlorhexidine improve outcomes in non-surgical management of peri-implant mucositis or peri-implantitis? : a systematic review and meta-analysis

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dc.contributor.author Liu, Siyan es
dc.contributor.author Li, Min es
dc.contributor.author Yu, Jianfeng es
dc.date.accessioned 2021-01-15T12:31:37Z
dc.date.available 2021-01-15T12:31:37Z
dc.date.issued 2020 es
dc.identifier.uri https://hdl.handle.net/10550/77188
dc.description.abstract With greater number of implants being placed in clinical practice, incidence of peri-implant diseases are on the rise. It is not known whether chlorhexidine (CHX) improves outcomes in the management of peri-implant diseases. The aim of this systematic review and meta-analysis was to evaluate the role of CHX in improving outcomes with non-surgical management of peri-implant mucositis and peri-implantitis. An electronic search of PubMed, Scopus, Embase, and CENTRAL (Cochrane Central Register of Controlled Trials) databases up to 1st August 2019 was carried out to search for studies evaluating the efficacy of CHX for non-surgical management of peri-implant diseases. Seven studies were included. Four studies evaluated the role of CHX in peri-implant mucositis and three in peri-implantitis. Oral prophylaxis with mechanical cleansing of implant surface prior to CHX use was carried out in all seven studies. Meta-analysis indicated that use of CHX did not improve probing depths in peri-implant mucositis (SMD= 0.11; 95% CI: -0.16 to 0.38; p=0.42, I2= 0%). Similarly, CHX did not significantly reduce probing depths in patients with peri-implantitis (MD= 1.57; 95% CI: -0.88 to 4.0; p=0.21, I2= 98%). Results on the efficacy of CHX in reducing BOP in peri-implantitis are conflicting. Results of our study indicate that adjunctive therapy with CHX may not improve outcomes with non-surgical management of peri-implant mucositis. Conclusions with regards to its role in non-surgical management of peri-implantitis cannot be drawn. There is a need for more homogenous RCTs with large sample size to define the role of CHX in non-surgical management of peri-implant mucositis and peri-implantitis. es
dc.source Liu, Siyan ; Li, Min ; Yu, Jianfeng. Does chlorhexidine improve outcomes in non-surgical management of peri-implant mucositis or peri-implantitis? : a systematic review and meta-analysis. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 25 5 2020: 18- es
dc.title Does chlorhexidine improve outcomes in non-surgical management of peri-implant mucositis or peri-implantitis? : a systematic review and meta-analysis es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.23633 es

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