Chemical aspects of human and environmental overload with fluorine
NAGIOS: RODERIC FUNCIONANDO

Chemical aspects of human and environmental overload with fluorine

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Chemical aspects of human and environmental overload with fluorine

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dc.contributor.author Han, Jianlin
dc.contributor.author Kiss, Loránd
dc.contributor.author Mei, Haibo
dc.contributor.author Remete, Attila Márió
dc.contributor.author Ponikvar-Svet, Maja
dc.contributor.author Sedgwick, Daniel Mark
dc.contributor.author Roman, Raquel
dc.contributor.author Fustero Lardiés, Santos
dc.contributor.author Moriwaki, Hiroki
dc.contributor.author Soloshonok, Vadim A.
dc.date.accessioned 2022-05-10T13:55:33Z
dc.date.available 2022-05-10T13:55:33Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/10550/82708
dc.description.abstract Over the last 100−120 years, due to the ever-increasing importance of fluorine-containing compounds in modern technology and daily life, the explosive development of the fluorochemical industry led to an enormous increase of emission of fluoride ions into the biosphere. This made it more and more important to understand the biological activities, metabolism, degradation, and possible environmental hazards of such substances. This comprehensive and critical review focuses on the effects of fluoride ions and organofluorine compounds (mainly pharmaceuticals and agrochemicals) on human health and the environment. To give a better overview, various connected topics are also discussed: reasons and trends of the advance of fluorine-containing pharmaceuticals and agrochemicals, metabolism of fluorinated drugs, withdrawn fluorinated drugs, natural sources of organic and inorganic fluorine compounds in the environment (including the biosphere), sources of fluoride intake, and finally biomarkers of fluoride exposure.
dc.language.iso eng
dc.relation.ispartof Chemical Reviews, 2021, vol. 121, num. 8, p. 4678-4742
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Han, Jianlin Kiss, Loránd Mei, Haibo Remete, Attila Márió Ponikvar-Svet, Maja Sedgwick, Daniel Mark Roman, Raquel Fustero Lardiés, Santos Moriwaki, Hiroki Soloshonok, Vadim A. 2021 Chemical aspects of human and environmental overload with fluorine Chemical Reviews 121 8 4678 4742
dc.subject Química farmacèutica
dc.subject Pèptids
dc.title Chemical aspects of human and environmental overload with fluorine
dc.type info:eu-repo/semantics/article
dc.date.updated 2022-05-10T13:55:34Z
dc.identifier.doi https://doi.org/10.1021/acs.chemrev.0c01263
dc.identifier.idgrec 152644

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