The EUropean Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI): Incidence and First-Episode Case-Control Programme. Soc Psychiatry Psychiatr Epidemiol
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The EUropean Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI): Incidence and First-Episode Case-Control Programme. Soc Psychiatry Psychiatr Epidemiol

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The EUropean Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI): Incidence and First-Episode Case-Control Programme. Soc Psychiatry Psychiatr Epidemiol

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dc.contributor.author Gayer-Anderson, Charlotte
dc.contributor.author Jongsma, Hannah
dc.contributor.author Di Forti, Marta
dc.contributor.author Quattrone, Diego
dc.contributor.author Velthorst, Eva
dc.contributor.author De Haan, Lieuwe
dc.contributor.author Selten, Jean-Paul
dc.contributor.author Szoke, Andrei
dc.contributor.author Llorca, Pierre-Michel
dc.contributor.author Tortelli, Andrea
dc.contributor.author Arango, Celso
dc.contributor.author Bobes, Julio
dc.contributor.author Bernardo, Miguel
dc.contributor.author Sanjuán Arias, Julio
dc.contributor.author Santos, Jose Luis
dc.contributor.author Arrojo, Manuel
dc.contributor.author Parellada, Mara
dc.contributor.author Tarricone, Ilaria
dc.contributor.author Berardi, Domenico
dc.contributor.author Ruggeri, Mirella
dc.contributor.author Lasalvia, Antonio
dc.contributor.author Ferraro, Laura
dc.contributor.author La Cascia, Caterina
dc.contributor.author La Barbera, Daniele
dc.contributor.author Menezes, Paulo Rossi
dc.contributor.author Del‑Ben, Cristina Marta
dc.contributor.author Rutten, Bart P.F.
dc.contributor.author van Os, J.
dc.contributor.author Jones, Peter B.
dc.contributor.author Murray, Robin
dc.contributor.author Kirkbride, James B.
dc.contributor.author Morgan, Craig
dc.contributor.author Lorente Rovira, Esther
dc.date.accessioned 2021-07-27T15:38:16Z
dc.date.available 2021-07-27T15:38:16Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/10550/80045
dc.description.abstract Purpose: The EUropean Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI) study contains an unparalleled wealth of comprehensive data that allows for testing hypotheses about (1) variations in incidence within and between countries, including by urbanicity and minority ethnic groups; and (2) the role of multiple environmental and genetic risk factors, and their interactions, in the development of psychotic disorders. Methods: Between 2010 and 2015, we identified 2774 incident cases of psychotic disorders during 12.9 million person-years at risk, across 17 sites in 6 countries (UK, The Netherlands, France, Spain, Italy, and Brazil). Of the 2774 incident cases, 1130 cases were assessed in detail and form the case sample for case-control analyses. Across all sites, 1497 controls were recruited and assessed. We collected data on an extensive range of exposures and outcomes, including demographic, clinical (e.g. premorbid adjustment), social (e.g. childhood and adult adversity, cannabis use, migration, discrimination), cognitive (e.g. IQ, facial affect processing, attributional biases), and biological (DNA via blood sample/cheek swab). We describe the methodology of the study and some descriptive results, including representativeness of the cohort. Conclusions: This resource constitutes the largest and most extensive incidence and case-control study of psychosis ever conducted.
dc.language.iso spa
dc.relation.ispartof Social Psychiatry and Psychiatric Epidemiology, 2020, vol. 55, num. 5, p. 645-657
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Gayer-Anderson, Charlotte Jongsma, Hannah Di Forti, Marta Quattrone, Diego Velthorst, Eva De Haan, Lieuwe Selten, Jean-Paul Szoke, Andrei Llorca, Pierre-Michel Tortelli, Andrea Arango, Celso Bobes, Julio Bernardo, Miguel Sanjuán Arias, Julio Santos, Jose Luis Arrojo, Manuel Parellada, Mara Tarricone, Ilaria Berardi, Domenico Ruggeri, Mirella Lasalvia, Antonio Ferraro, Laura La Cascia, Caterina La Barbera, Daniele Menezes, Paulo Rossi Del&#8209Ben, Cristina Marta Rutten, Bart P.F. van Os, J. Jones, Peter B. Murray, Robin Kirkbride, James B. Morgan, Craig Lorente Rovira, Esther 2020 The EUropean Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI): Incidence and First-Episode Case-Control Programme. Soc Psychiatry Psychiatr Epidemiol Social Psychiatry and Psychiatric Epidemiology 55 5 645 657
dc.subject Esquizofrènia
dc.title The EUropean Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI): Incidence and First-Episode Case-Control Programme. Soc Psychiatry Psychiatr Epidemiol
dc.type info:eu-repo/semantics/article
dc.date.updated 2021-07-27T15:38:17Z
dc.identifier.doi https://doi.org/10.1007/s00127-020-01831-x
dc.identifier.idgrec 145576

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