Rational chemical multifunctionalization of graphene interface enhances targeted cancer therapy
NAGIOS: RODERIC FUNCIONANDO

Rational chemical multifunctionalization of graphene interface enhances targeted cancer therapy

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Rational chemical multifunctionalization of graphene interface enhances targeted cancer therapy

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dc.contributor.author Lucherelli, Matteo Andrea
dc.contributor.author Yu, Yue
dc.contributor.author Reina, Giacomo
dc.contributor.author Abellán Sáez, Gonzalo
dc.contributor.author Miyako, Eijiro
dc.contributor.author Bianco, Alberto
dc.date.accessioned 2021-04-26T14:45:41Z
dc.date.available 2021-04-26T14:45:41Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/10550/78920
dc.description.abstract The synthesis of a drug delivery platform based on graphene was achieved through a step‐by‐step strategy of selective amine deprotection and functionalization. The multifunctional graphene platform, functionalized with indocyanine green, folic acid, and doxorubicin showed an enhanced anticancer activity. The remarkable targeting capacity for cancer cells in combination with the synergistic effect of drug release and photothermal properties prove the great advantage of a combined chemo‐ and phototherapy based on graphene against cancer, opening the doors to future therapeutic applications of this type of material.
dc.language.iso eng
dc.relation.ispartof Angewandte Chemie, 2020, vol. 132, num. 33, p. 14138-14143
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Lucherelli, Matteo Andrea Yu, Yue Reina, Giacomo Abellán Sáez, Gonzalo Miyako, Eijiro Bianco, Alberto 2020 Rational chemical multifunctionalization of graphene interface enhances targeted cancer therapy Angewandte Chemie 132 33 14138 14143
dc.subject Materials
dc.subject Càncer
dc.title Rational chemical multifunctionalization of graphene interface enhances targeted cancer therapy
dc.type info:eu-repo/semantics/article
dc.date.updated 2021-04-26T14:45:42Z
dc.identifier.doi https://doi.org/10.1002/ange.201916112
dc.identifier.idgrec 145990

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