Risk factors related to oral candidiasis in patients with primary Sjögren?s syndrome
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Risk factors related to oral candidiasis in patients with primary Sjögren?s syndrome

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Risk factors related to oral candidiasis in patients with primary Sjögren?s syndrome

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dc.contributor.author Serrano, Julia es
dc.contributor.author López-Pintor Muñoz, Rosa Mª es
dc.contributor.author Ramírez Martínez Acitores, Lucía es
dc.contributor.author Fernández Castro, Mónica es
dc.contributor.author Sanz Alonso, Mariano es
dc.contributor.author Melchor, Sheila es
dc.contributor.author Peiteado López, Diana es
dc.contributor.author Hernández Vallejo, Gonzalo es
dc.date.accessioned 2021-01-15T12:29:43Z
dc.date.available 2021-01-15T12:29:43Z
dc.date.issued 2020 es
dc.identifier.uri https://hdl.handle.net/10550/77182
dc.description.abstract Candidiasis is the most frequent mycotic infection of the oral cavity. The aim of this study was to investigate the presence of clinical oral candidiasis and Candida albicans yeast in a population diagnosed of primary Sjögren?s syndrome (pSS) and to study the possible factors associated with this infection. An observational cross-sectional study was conducted in 61 pSS patients (60 women, 1 man, mean age 57.64±13.52) where patient based information (demographic and medical, tobacco and alcohol consumption history), intraoral parameters (presence of dentures, clinical signs of candidiasis), salivary analytical information (number of Candida albicans as colony-forming units per millilitre (CFU/mL), salivary pH levels, unstimulated whole saliva (UWS) and stimulated whole saliva (SWS) were collected. 13.1% of pSS patients presented oral signs of candidiasis. Denture stomatitis and angular cheilitis were the most common lesions. 87.5% of patients with clinical candidiasis presented reduced pH levels and salivary flow in both UWS and SWS. A significant statistical negative correlation was found between CFU/mL of Candida albicans and levels of UWS and SWS. A negative correlation was found between pH levels and CFU/mL, although not statistically significant. A reduced salivary flow may predispose pSS patients to Candida albicans overgrowth, which may show with clinical signs. Preventive measures are of great importance to avoid and to treat this condition promptly. es
dc.source Serrano, Julia ; López-Pintor Muñoz, Rosa Mª ; Ramírez Martínez Acitores, Lucía ; Fernández Castro, Mónica ; Sanz Alonso, Mariano ; Melchor, Sheila ; Peiteado López, Diana ; Hernández Vallejo, Gonzalo. Risk factors related to oral candidiasis in patients with primary Sjögren?s syndrome. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 25 5 2020: 12- es
dc.title Risk factors related to oral candidiasis in patients with primary Sjögren?s syndrome es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.23719 es

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