Head and neck squamous cell carcinoma in young patients : a 26-year clinicopathologic retrospective study in a Brazilian specialized center
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Head and neck squamous cell carcinoma in young patients : a 26-year clinicopathologic retrospective study in a Brazilian specialized center

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Head and neck squamous cell carcinoma in young patients : a 26-year clinicopathologic retrospective study in a Brazilian specialized center

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dc.contributor.author Tomo, Saygo es
dc.contributor.author Neto, Sebastião Conrado es
dc.contributor.author Collado, Francisco Urbano es
dc.contributor.author Sundefeld, Maria L.M.M. es
dc.contributor.author Bernabé, Daniel Galera es
dc.contributor.author Biasoli, Éder Ricardo es
dc.contributor.author Miyahara, Glauco Issamu es
dc.date.accessioned 2021-01-15T09:07:42Z
dc.date.available 2021-01-15T09:07:42Z
dc.date.issued 2020 es
dc.identifier.uri https://hdl.handle.net/10550/77140
dc.description.abstract To describe the clinicopathologic profile of young patients with head and neck squamous cell carcinoma (HNSCC) and compare to middle-aged and elderly adults. Patients? individual records were reviewed for clinicopathologic data. Eighty-nine patients with age 18-45 years old met the inclusion criteria of the study. Two additional groups of middle-aged (n=89) and old (n=89) adults were set to comparative analysis. Young patients represented 11.9% of all patients diagnosed with HNSCC. Women were more affected by HNSCC in the young and elder groups (p= 0.04), and young patients were more prone to be non-smokers (p= 0.01) and have lymph node metastasis at the time of diagnosis (p=0.04). In the young group, patients diagnosed with the disease in advanced stages were more prone to have a positive familial history of cancer (p= 0.04), a positive status of alcohol consumption (p= 0.03), and to be heavy drinkers (p= 0.01). Survival was not different for the young group in comparison to the other groups. HNSCC in young patients had a different profile when compared to older patients, especially regarding sex and exposure to the classic risk factors for this disease. The survival of the young group is similar to the older groups and advanced clinical stage is predictor of worse survival. es
dc.source Tomo, Saygo ; Neto, Sebastião Conrado ; Collado, Francisco Urbano ; Sundefeld, Maria L.M.M. ; Bernabé, Daniel Galera ; Biasoli, Éder Ricardo ; Miyahara, Glauco Issamu. Head and neck squamous cell carcinoma in young patients : a 26-year clinicopathologic retrospective study in a Brazilian specialized center. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 25 3 2020: 17- es
dc.title Head and neck squamous cell carcinoma in young patients : a 26-year clinicopathologic retrospective study in a Brazilian specialized center es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.23461 es

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