Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy
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Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy

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Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy

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dc.contributor.author San Martín Valenzuela, Constanza
dc.contributor.author Borras Barrachina, Aroa
dc.contributor.author Gallego, Juan José
dc.contributor.author Urios, Amparo
dc.contributor.author Mestre Salvador, Víctor
dc.contributor.author Correa Ghisays, Patricia María
dc.contributor.author Ballester, María Pilar
dc.contributor.author Escudero García, Desamparados
dc.contributor.author Tosca, Joan
dc.contributor.author Montón, Cristina
dc.contributor.author Ríos, María Pilar
dc.contributor.author Kosenko, Elena
dc.contributor.author Felipo Orts, Vicente
dc.contributor.author Tabares Seisdedos, Rafael
dc.contributor.author Selva Vera, Gabriel
dc.contributor.author Montoliu, Carmina
dc.date.accessioned 2020-11-25T19:09:14Z
dc.date.available 2020-11-25T19:09:14Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/10550/76493
dc.description.abstract Minimal hepatic encephalopathy (MHE) is associated with mild cognitive impairment and frailty. This study aims to identify cognitive and motor differences in cirrhotic patients with and without MHE, and the correlations between motor signs and cognitive performance. Gait, balance, hand strength and motor speed performance were evaluated in 66 cirrhotic patients (38 without and 28 with MHE, according to the Psychometric Hepatic Encephalopathy Score (PHES). Cognitive performance was measured with the Mini-Mental State Examination, Verbal Fluency Test, Aprendizaje Verbal España-Complutense Test (TAVEC), Wechsler Adult Intelligence Scale III, Hamilton Depression and Anxiety Rating Scale and Functioning Assessment Short Test (FAST). MHE patients performed worse than patients without MHE in cognitive and autonomous functioning, learning and long-term memory, and verbal fluency. The same pattern was found in gait, center of pressure movement, variability of hand strength performance and hand motor speed. In MHE patients, high correlations were found between balance and FAST test, gait velocity and verbal skills, hand strength variability and anxiety and depression, and motor speed and FAST and TAVEC. MHE patients showed worse motor and cognitive performance than patients without MHE. MHE patients could have impaired movement control expressed as bradykinesia, and this reduced motor performance could correlate with cognitive performance.
dc.language.iso eng
dc.relation.ispartof Journal Of Clinical Medicine, 2020
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source San Martín Valenzuela, Constanza Borras Barrachina, Aroa Gallego, Juan José Urios, Amparo Mestre Salvador, Víctor Correa Ghisays, Patricia María Ballester, María Pilar Escudero García, Desamparados Tosca, Joan Montón, Cristina Ríos, María Pilar Kosenko, Elena Felipo, Vicente Tabares Seisdedos, Rafael Selva Vera, Gabriel Montoliu, Carmina 2020 Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy Journal Of Clinical Medicine
dc.subject Cirrosi hepàtica
dc.subject Aprenentatge, Aptitud per a l' Tests
dc.subject Aprenentatge motor
dc.title Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy
dc.type info:eu-repo/semantics/article
dc.date.updated 2020-11-25T19:09:15Z
dc.identifier.doi https://doi.org/10.3390/jcm9072154
dc.identifier.idgrec 141482

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