pBrain: A novel pipeline for Parkinson related brain structure segmentation
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pBrain: A novel pipeline for Parkinson related brain structure segmentation

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pBrain: A novel pipeline for Parkinson related brain structure segmentation

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dc.contributor.author Manjón, José Vicente
dc.contributor.author Bertó, Alexa
dc.contributor.author Romero, José E.
dc.contributor.author Lanuza Navarro, Enrique
dc.contributor.author Vivo-Hernando, Roberto
dc.contributor.author Aparici Robles, Fernando
dc.contributor.author Coupé, Pierrick
dc.date.accessioned 2020-03-04T14:56:17Z
dc.date.available 2020-03-04T14:56:17Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/10550/73412
dc.description.abstract Parkinson is a very prevalent neurodegenerative disease impacting the life of millions of people worldwide. Although its cause remains unknown, its functional and structural analysis is fundamental to advance in the search of a cure or symptomatic treatment. The automatic segmentation of deep brain structures related to Parkinson`s disease could be beneficial for the follow up and treatment planning. Unfortunately, there is not broadly available segmentation software to automatically measure Parkinson related structures. In this paper, we present a novel pipeline to segment three deep brain structures related to Parkinson's disease (substantia nigra, subthalamic nucleus and red nucleus). The proposed method is based on the multi-atlas label fusion technology that works on standard and high-resolution T2-weighted images. The proposed method also includes as post-processing a new neural network-based error correction step to minimize systematic segmentation errors. The proposed method has been compared to other state-of-the-art methods showing competitive results in terms of accuracy and execution time.
dc.language.iso eng
dc.relation.ispartof Neuroimage-Clinical, 2020, vol. 25, p. 102184
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Manjón, José Vicente Bertó, Alexa Romero, José E. Lanuza Navarro, Enrique Vivo-Hernando, Roberto Aparici Robles, Fernando Coupé, Pierrick 2020 pBrain: A novel pipeline for Parkinson related brain structure segmentation Neuroimage-Clinical 25 102184
dc.subject Sistema nerviós Malalties
dc.subject Neurologia
dc.title pBrain: A novel pipeline for Parkinson related brain structure segmentation
dc.type info:eu-repo/semantics/article
dc.date.updated 2020-03-04T14:56:17Z
dc.identifier.doi https://doi.org/10.1016/j.nicl.2020.102184
dc.identifier.idgrec 136586

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