Stem cell paracrine actions in tissue regeneration and its potential therapeutic effect in human endometrium: a retrospective study.
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Stem cell paracrine actions in tissue regeneration and its potential therapeutic effect in human endometrium: a retrospective study.

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Stem cell paracrine actions in tissue regeneration and its potential therapeutic effect in human endometrium: a retrospective study.

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dc.contributor.author de Miguel, Lucía
dc.contributor.author Ferrero, Hortensia
dc.contributor.author López Martínez, Sara
dc.contributor.author Campo, Hannes
dc.contributor.author López Pérez, Nuria
dc.contributor.author Faus, Amparo
dc.contributor.author Hervás, David
dc.contributor.author Santamaría, Xavier
dc.contributor.author Pellicer, Antonio
dc.contributor.author Cervelló Alcaraz, Irene
dc.date.accessioned 2020-01-15T11:01:15Z
dc.date.available 2020-01-15T11:01:15Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/10550/72569
dc.description.abstract Objective: Determining genetic and paracrine mechanisms behind endometrial regeneration in Asherman's Syndrome and Endometrial Atrophy (AS/EA) patients after autologous CD133+ bone marrow-derived stem cells (CD133+BMDSCs) transplantation. Design: Retrospective study using human endometrial biopsies and mouse models. Setting: Fundación-IVI, IIS-La Fe, Valencia, Spain. Samples: Endometrial biopsies collected before and after CD133+BMDSCs therapy, from 8 women with AS/EA (NCT02144987). And uterus from 5 mice, with only left horns receiving CD133+BMDSCs therapy. Methods: In human samples, hematoxylin and eosin (H&E) staining, RNA arrays, PCR validation and neutrophil elastase (NE) immunohistochemistry (IHQ). In mouse samples, PCR validation and protein immunoarrays.
dc.relation.ispartof BJOG-An International Journal of Obstetrics and Gynaecology, 2020
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source de Miguel, Lucía Ferrero, Hortensia López Martínez, Sara Campo, Hannes López Pérez, Nuria Faus, Amparo Hervás, David Santamaría, Xavier Pellicer, Antonio Cervelló Alcaraz, Irene 2020 Stem cell paracrine actions in tissue regeneration and its potential therapeutic effect in human endometrium: a retrospective study. BJOG-An International Journal of Obstetrics and Gynaecology
dc.title Stem cell paracrine actions in tissue regeneration and its potential therapeutic effect in human endometrium: a retrospective study.
dc.type info:eu-repo/semantics/article
dc.date.updated 2020-01-15T11:01:15Z
dc.identifier.idgrec 135707

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