Clickable poly-L-lysine for the formation of biorecognition surfaces
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Clickable poly-L-lysine for the formation of biorecognition surfaces

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Clickable poly-L-lysine for the formation of biorecognition surfaces

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dc.contributor.author Di Iorio, Daniele
dc.contributor.author Martí Morant, Almudena
dc.contributor.author Koeman, Sander
dc.contributor.author Huskens, Jurriaan
dc.date.accessioned 2019-11-11T15:40:46Z
dc.date.available 2019-11-11T15:40:46Z
dc.date.issued 2019
dc.identifier.uri https://hdl.handle.net/10550/72168
dc.description.abstract Biomolecules are immobilized onto surfaces employing the fast and stable adsorption of poly-L-lysine (PLL) polymers and the versatile copper-free click chemistry reactions. This method provides the combined advantages of versatile surface adsorption with density control using polyelectrolytes and of the covalent and orthogonal immobilization of biomolecules with higher reaction rates and improved yields of click chemistry. Using DNA attachment as a proof of concept, control over the DNA probe density and applicability in electrochemical detection are presented.
dc.language.iso eng
dc.relation.ispartof Rsc Advances, 2019, vol. 9, num. 61, p. 35608-35613
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Di Iorio, Daniele Martí Morant, Almudena Koeman, Sander Huskens, Jurriaan 2019 Clickable poly-L-lysine for the formation of biorecognition surfaces Rsc Advances 9 61 35608 35613
dc.subject Biomolècules
dc.subject ADN
dc.title Clickable poly-L-lysine for the formation of biorecognition surfaces
dc.type info:eu-repo/semantics/article
dc.date.updated 2019-11-11T15:40:47Z
dc.identifier.doi https://doi.org/10.1039/C9RA08714A
dc.identifier.idgrec 135066

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