Catalytic Enantioselective Addition of Me2Zn to Isatins
NAGIOS: RODERIC FUNCIONANDO

Catalytic Enantioselective Addition of Me2Zn to Isatins

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Catalytic Enantioselective Addition of Me2Zn to Isatins

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Vila Descals, Carlos; Del Campo, Andrés; Blay Llinares, Gonzalo Perfil; Pedro, José Ramón
This document is a artículoDate2017
Chiral α-hydroxyamide L5 derived from (S)-(+)-mandelic acid catalyzes the enantioselective addition of dimethylzinc to isatins affording the corresponding chiral 3-hydroxy-3-methyl-2-oxindoles with good yields and er up to 90:10. Furthermore, several chemical transformations were performed with the 3-hydroxy-2-oxindoles obtained.

    Vila Descals, Carlos Del Campo, Andrés Blay Llinares, Gonzalo Pedro, José Ramón 2017 Catalytic Enantioselective Addition of Me2Zn to Isatins Catalysts 7 12 387
https://doi.org/10.3390/catal7120387

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