Tongue metastasis of cutaneous melanoma : report of two cases and literature review
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Tongue metastasis of cutaneous melanoma : report of two cases and literature review

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Tongue metastasis of cutaneous melanoma : report of two cases and literature review

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dc.contributor.author Markman, Renata Lucena es
dc.contributor.author Rosa, Giuliano-Augusto-Belizario es
dc.contributor.author Cardili, Leonardo es
dc.contributor.author Simonato, Luciana Estevam es
dc.contributor.author Brandao, Thais-Bianca es
dc.contributor.author Ribeiro, Ana-Carolina-Prado es
dc.date.accessioned 2019-03-07T11:03:27Z
dc.date.available 2019-03-07T11:03:27Z
dc.date.issued 2018 es
dc.identifier.uri http://hdl.handle.net/10550/69416
dc.description.abstract Malignant metastases to the oral cavity are rare and metastatic melanomas of the tongue are considered exceptionally uncommon, with less than 10 cases published in the English literature so far. Two female patients in the 7th decade of life presented to our dental service with nodules in the tongue. Both patients had multiple metastases at the time of oral diagnosis and primary melanoma originated on the skin. An intra-oral incisional biopsy was performed under local anesthesia and the histopathologic analysis was characterized by the proliferation of atypical epithelioid cells displaying a poorly delimited cytoplasm and hyperchromatic nucleus which contained eosinophilic macronucleoli. Immunohistochemistry was performed in both cases to confirm the clinical hypothesis of metastatic melanoma. After the diagnosis of oral metastatic melanoma, the patients were maintained under palliative care and close medical follow-up. Both patients died four and a half months and 20 months after the diagnosis of tongue metastasis. Although rare, metastatic melanoma should be included in the differential diagnosis of tongue lesions detected in patients with a previous medical history of cutaneous melanoma. es
dc.source Markman, Renata Lucena ; Rosa, Giuliano-Augusto-Belizario ; Cardili, Leonardo ; Simonato, Luciana Estevam ; Brandao, Thais-Bianca ; Ribeiro, Ana-Carolina-Prado. Tongue metastasis of cutaneous melanoma : report of two cases and literature review. En: Journal of Clinical and Experimental Dentistry, 10 11 2018: 1130-1134 es
dc.title Tongue metastasis of cutaneous melanoma : report of two cases and literature review es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.54980 es

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