Sen, Rickdeb; Escorihuela Fuentes, Jorge; van Delft, Floris L.; Zuilhof, Han | |
This document is a artículoDate2017 | |
Este documento está disponible también en : http://hdl.handle.net/10550/67411 |
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Strain‐promoted oxidation‐controlled cyclooctyne‐1,2‐quinone cycloaddition (SPOCQ) between functionalized bicyclo[6.1.0]non‐4‐yne (BCN) and surface‐bound quinones revealed an unprecedented 100 % conjugation efficiency. In addition, monitoring by direct analysis in real time mass spectrometry (DART‐MS) revealed the underlying kinetics and activation parameters of this immobilization process in dependence on its microenvironment. | |
Sen, Rickdeb Escorihuela Fuentes, Jorge van Delft, Floris L. Zuilhof, Han 2017 Rapid and Complete Surface Modification with Strain‐Promoted Oxidation‐Controlled Cyclooctyne‐1,2‐Quinone Cycloaddition (SPOCQ) Angewandte Chemie 56 12 3299 3303 |
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https://doi.org/10.1002/anie.201612037 |