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Impact of the anatomical location, alcoholism and smoking on the prevalence of advanced oral cancer in Brazil

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Impact of the anatomical location, alcoholism and smoking on the prevalence of advanced oral cancer in Brazil

dc.contributor.author	Bezerra, Natanael-Victor-Furtunato	es
dc.contributor.author	Leite, Karla-Lorene-de França	es
dc.contributor.author	de Medeiros, Mariana-Marinho-Davino	es
dc.contributor.author	Martins, Mariana-Leonel	es
dc.contributor.author	Cardoso, Andrea-Medeiros-Rodrigues	es
dc.contributor.author	Alves, Pollianna-Muniz	es
dc.contributor.author	Padilha, Wilton-Wilney-Nascimento	es
dc.contributor.author	Cavalcanti, Yuri-Wanderley	es
dc.date.accessioned	2018-05-28T10:45:22Z
dc.date.available	2018-05-28T10:45:22Z
dc.date.issued	2018	es
dc.identifier.uri	http://hdl.handle.net/10550/66435
dc.description.abstract	To evaluate the prevalence of oral cancer in Brazil according to the clinical stage, anatomical location, alcoholism and smoking. Data referring to 31,217 cases of oral cancer, from 2000 to 2010, were obtained from the Integrator Module of the Hospital Registry of Cancer. Inconsistent data (?non-classified? cases) was eliminated and 21,160 cases were analyzed. The frequency distribution according to clinical stage, anatomical location, alcoholism and smoking was analyzed descriptively and through a binary logistic regression model (?<0.05). The clinical stage (dependent variable) was dichotomized in early stage (I and II) or advanced stage (III and IV). The year of diagnosis, anatomical location and deleterious habits (alcoholism and smoking) were considered independent variables. The most frequent characteristics were: oropharynx location (n=3856, 18.41%), clinical stage IV (n=11924, 56.09%) and combined use of alcohol and tobacco (n=19226; 61.59%). The year 2009 (p<0.01, PR = 1.162, CI-95%=1.053-1.283) and location at the base of tongue (p<0.01, PR = 2.485, CI-95% = 2.182-2.807) presented a higher prevalence ratio for advanced stage oral cancer. The combined use of alcohol and tobacco showed a higher prevalence rate for the advanced clinical stage of cancer (p<0.01, PR =1.449, CI-95%=1.382-1.520) if compared to individuals without habits, or just alcoholics. Higher prevalence of advanced stage of oral cancer is related to the localization at the base of the tongue and to the concomitant use of alcohol and tobacco. Therefore, it can be suggested that all these characteristics lead to a worse prognosis of oral cancer.	es
dc.source	Bezerra, Natanael-Victor-Furtunato ; Leite, Karla-Lorene-de França ; de Medeiros, Mariana-Marinho-Davino ; Martins, Mariana-Leonel ; Cardoso, Andrea-Medeiros-Rodrigues ; Alves, Pollianna-Muniz ; Padilha, Wilton-Wilney-Nascimento ; Cavalcanti, Yuri-Wanderley. Impact of the anatomical location, alcoholism and smoking on the prevalence of advanced oral cancer in Brazil. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 23 3 2018: 7-	es
dc.title	Impact of the anatomical location, alcoholism and smoking on the prevalence of advanced oral cancer in Brazil	es
dc.type	info:eu-repo/semantics/article	en
dc.type	info:eu-repo/semantics/publishedVersion	en
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.22318	es