Dental approach for Apert syndrome in children : a systematic review
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Dental approach for Apert syndrome in children : a systematic review

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Dental approach for Apert syndrome in children : a systematic review

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dc.contributor.author López-Estudillo, Andrea-Stacy es
dc.contributor.author Rosales Bérber, Miguel Ángel es
dc.contributor.author Ruiz Rodríguez, Socorro es
dc.contributor.author Pozos Guillén, Amaury de Jesús es
dc.contributor.author Noyola Frías, Miguel Angel es
dc.contributor.author Garrocho Rangel, Arturo es
dc.date.accessioned 2018-05-02T12:04:09Z
dc.date.available 2018-05-02T12:04:09Z
dc.date.issued 2017 es
dc.identifier.uri http://hdl.handle.net/10550/65933
dc.description.abstract Apert Syndrome (AS), or type I acrocephalosyndactyly, is a rare, congenital craniosynostosis condition resulting from missense mutations in the gene encoding fibroblast growth factor receptor 2. It is characterized by three specific clinical features: brachycephalic skull; midface hypoplasia, and limb abnormalities (syndactyly of hands and feet). The disorder exhibits variable presentations in bones, brain, skin, internal organs, and in the oral/maxillofacial region. The aim of the present paper was to show the main results from a systematic review of AS. A search of the literature was performed from April to June 2016 in five electronic databases. Clinical interventional or observational studies, reviews, and case reports were included. The present systematic review was carried out strictly following PRISMA and Cochrane Collaboration criteria. A total of 129 potential references were identified. After reviewing titles and abstracts, 77 of these did not meet the desired criteria and were discarded. The full text of the remaining 52 manuscripts was critically screened. Finally, 35 relevant papers were identified for inclusion in the present systematic review and classified according to topic type. According to the information gathered, dentistry practitioners must be able to supply an early diagnosis through the recognition of AS clinical features and provide correct oral management. Additionally, they should be integrated in a multidisciplinary medical care team in order to improve the quality of life of the affected patients. es
dc.source López-Estudillo, Andrea-Stacy ; Rosales Bérber, Miguel Ángel ; Ruiz Rodríguez, Socorro ; Pozos Guillén, Amaury de Jesús ; Noyola Frías, Miguel Angel ; Garrocho Rangel, Arturo. Dental approach for Apert syndrome in children : a systematic review. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 22 6 2017: 1- es
dc.title Dental approach for Apert syndrome in children : a systematic review es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.21628 es

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