Bisphosphonate-associated osteonecrosis of the jaw : a proposal for conservative treatment
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Bisphosphonate-associated osteonecrosis of the jaw : a proposal for conservative treatment

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Bisphosphonate-associated osteonecrosis of the jaw : a proposal for conservative treatment

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dc.contributor.author Bocanegra Pérez, Sacramento es
dc.contributor.author Vicente Barrero, Mario es
dc.contributor.author Sosa Hernández, Manuel es
dc.contributor.author Knezevic, Milan es
dc.contributor.author Castellano Navarro, José María es
dc.contributor.author Rodríguez Millares, José es
dc.date.accessioned 2017-12-16T11:53:02Z
dc.date.available 2017-12-16T11:53:02Z
dc.date.issued 2008 es
dc.identifier.uri http://hdl.handle.net/10550/63665
dc.description.abstract The use of bisphosphonates (BPs) has proven effective in the treatment of bone-related diseases, despite the potential risk of developing osteonecrosis of the jaw (ONJ). So far, results for the treatment of ONJ have not been satisfactory. In our study, we have treated two patients diagnosed with ONJ. In addition to local treatments a hydrogel was applied, with promising results. The fistulae disappeared 2-3 weeks into the treatment. After a six-month follow-up period there has been no sign of recurrence. The extent of maxillary bone exposure has diminished notably, although not entirely disappeared. In all cases, the patients exhibit no other symptoms (they suffer from no pain or swelling or functional impotence). For this reason we believe this protocol might be useful in the case of patients who suffer from pain and fistulation secondary to BP-associated ONJ to improve the state of their lesions until definitive treatment can be undertaken. Although these findings are not conclusive, given that we are reporting data on two patients only, we believe that this might be an alternative treatment in refractory cases where other therapies are counter-indicated. A controlled randomized and prospective study would be required to confirm our findings. es
dc.source Bocanegra Pérez, Sacramento ; Vicente Barrero, Mario ; Sosa Hernández, Manuel ; Knezevic, Milan ; Castellano Navarro, José María ; Rodríguez Millares, José. Bisphosphonate-associated osteonecrosis of the jaw : a proposal for conservative treatment. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 13 12 2008: 5- es
dc.title Bisphosphonate-associated osteonecrosis of the jaw : a proposal for conservative treatment es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi es

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