Distribution of macrophages and plasma cells in apical periodontitis and their relationship with clinical and image data
NAGIOS: RODERIC FUNCIONANDO

Distribution of macrophages and plasma cells in apical periodontitis and their relationship with clinical and image data

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Distribution of macrophages and plasma cells in apical periodontitis and their relationship with clinical and image data

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dc.contributor.author Azeredo, Stéphane V. es
dc.contributor.author Brasil, Sabrina C. es
dc.contributor.author Antunes, Henrique es
dc.contributor.author Marques, Fábio V. es
dc.contributor.author Pires, Fábio-Ramôa es
dc.contributor.author Armada, Luciana es
dc.date.accessioned 2017-11-28T11:02:41Z
dc.date.available 2017-11-28T11:02:41Z
dc.date.issued 2017 es
dc.identifier.uri http://hdl.handle.net/10550/63363
dc.description.abstract Macrophages and plasma cells play a key role in the regulation of innate and adaptive immunity. The aim of this study was to assess the presence of these cells in apical periodontitis and their distribution comparing with clinical and image data. Thirty-three lesions were selected and divided in two groups (17 periapical cysts and 16 periapical granulomas). Immunoreactions using anti-CD68 and anti-CD138 antibodies were carried out; image analysis was performed with an optical microscope and 5 high-power fields from each slide were evaluated leading to an average score of immunoexpression. This mean score was compared between the two groups and correlated with the clinical and image data. There was no statistically significant difference (p >0.05) for the mean average score of CD68+ macrophages and CD138+ plasma cells when comparing the two groups (cysts x granulomas) and the specimens included in each specific group. No statistically significant differences (p >0.05) were also observed when comparing the average scores with clinical and image data. The presence of CD68+ macrophages and CD138+ plasma cells was similar in periapical cysts and granulomas and the presence of these cells did not correlate with clinical and image data from both groups. es
dc.source Azeredo, Stéphane V. ; Brasil, Sabrina C. ; Antunes, Henrique ; Marques, Fábio V. ; Pires, Fábio-Ramôa ; Armada, Luciana. Distribution of macrophages and plasma cells in apical periodontitis and their relationship with clinical and image data. En: Journal of Clinical and Experimental Dentistry, 9 9 2017: 1060-1065 es
dc.title Distribution of macrophages and plasma cells in apical periodontitis and their relationship with clinical and image data es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.53758 es

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