Melanotic neuroectodermal tumour of infancy : a case report and review of the aetiopathogenic hypotheses
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Melanotic neuroectodermal tumour of infancy : a case report and review of the aetiopathogenic hypotheses

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Melanotic neuroectodermal tumour of infancy : a case report and review of the aetiopathogenic hypotheses

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dc.contributor.author Madrid, Carlos es
dc.contributor.author Aziza, Jacqueline es
dc.contributor.author Hlali, Anasse es
dc.contributor.author Bouferrache, Kahina es
dc.contributor.author Abarca, Marcelo es
dc.date.accessioned 2017-07-27T06:54:04Z
dc.date.available 2017-07-27T06:54:04Z
dc.date.issued 2010 es
dc.identifier.uri http://hdl.handle.net/10550/60255
dc.description.abstract The case of a 2-month-old healthy infant without relevant medical history. The patient was referred due to the aggravation of a swelling occupying the left half of the anterior maxilla. This lesion became visible approximately one month ago; it involved the buccal gingiva and alveolar bone, including the deciduous tooth germs 6.1 and 6.2. The swelling had dimensions of 20 mm x 20 mm. The surgical excision was performed under general anesthesia. The tooth buds of 6.1 and 6.2 were closely related to the tumour and so were removed. The lesion was entirely enucleated. The pathology of the lesion confirmed a melanotic neuroectodermal tumour of infancy. The melanotic neuroectodermal tumour of infancy (MNTI) has been described as a rare benign pigmented painless swelling that usually occurs in the anterior region of the maxilla and in the incisor region. The histological examination showed small basophilic cells, many containing melanin pigmentation within the cytoplasm, with a second population of larger cubical cells with abundant cytoplasm, arranged in alveolar or adenoid clusters. According to Krompecher this tumour derives from epithelial nests evolved at the time of embryonic fusion of the facial processes. It has also been suggested that the tumour arises from the retinal anlage by a pinching-off process of neuroepithelium during the formation of embryonic eye. More recently, the presence of high levels of vanillylmandelic acid suggest a neural origin of the tumour. es
dc.source Madrid, Carlos ; Aziza, Jacqueline ; Hlali, Anasse ; Bouferrache, Kahina ; Abarca, Marcelo. Melanotic neuroectodermal tumour of infancy : a case report and review of the aetiopathogenic hypotheses. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 15 5 2010: 13- es
dc.title Melanotic neuroectodermal tumour of infancy : a case report and review of the aetiopathogenic hypotheses es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.15.e739 es

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