Gene therapy with growth factors for periodontal tissue engineering : a review
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Gene therapy with growth factors for periodontal tissue engineering : a review

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Gene therapy with growth factors for periodontal tissue engineering : a review

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dc.contributor.author Sood, Shaveta es
dc.contributor.author Gupta, Shipra es
dc.contributor.author Mahendra, Aneet es
dc.date.accessioned 2017-07-25T12:11:00Z
dc.date.available 2017-07-25T12:11:00Z
dc.date.issued 2012 es
dc.identifier.uri http://hdl.handle.net/10550/59977
dc.description.abstract The treatment of oral and periodontal diseases and associated anomalies accounts for a significant proportion of the healthcare burden, with the manifestations of these conditions being functionally and psychologically debilitating. A challenge faced by periodontal therapy is the predictable regeneration of periodontal tissues lost as a consequence of disease. Growth factors are critical to the development, maturation, maintenance and repair of oral tissues as they establish an extra-cellular environment that is conducive to cell and tissue growth. Tissue engineering principles aim to exploit these properties in the development of biomimetic materials that can provide an appropriate microenvironment for tissue development. The aim of this paper is to review emerging periodontal therapies in the areas of materials science, growth factor biology and cell/gene therapy. Various such materials have been formulated into devices that can be used as vehicles for delivery of cells, growth factors and DNA. Different mechanisms of drug delivery are addressed in the context of novel approaches to reconstruct and engineer oral and tooth supporting structure. © Medicina Oral. es
dc.source Sood, Shaveta ; Gupta, Shipra ; Mahendra, Aneet. Gene therapy with growth factors for periodontal tissue engineering : a review. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 17 2 2012: 1- es
dc.title Gene therapy with growth factors for periodontal tissue engineering : a review es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.17472 es

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