Efect of periodontal disease and non surgical periodontal treatment on C-reactive protein. Evaluation of type 1 diabetic patients
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Efect of periodontal disease and non surgical periodontal treatment on C-reactive protein. Evaluation of type 1 diabetic patients

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Efect of periodontal disease and non surgical periodontal treatment on C-reactive protein. Evaluation of type 1 diabetic patients

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dc.contributor.author Llambés Arenas, Fernando es
dc.contributor.author Silvestre Donat, Francisco Javier es
dc.contributor.author Hernández Mijares, Antonio es
dc.contributor.author Guiha, Rami es
dc.contributor.author Bautista, Daniel es
dc.contributor.author Caffesse, Raúl es
dc.date.accessioned 2017-07-24T12:12:42Z
dc.date.available 2017-07-24T12:12:42Z
dc.date.issued 2012 es
dc.identifier.uri http://hdl.handle.net/10550/59911
dc.description.abstract Objectives: The purpose of this study was to analyze how anti-infectious periodontal treatment affects C reactive protein (CRP) values in patients with type 1 diabetes, and correlate baseline CRP levels with periodontal disease severity. Study D esign: A cohort of fifty three subjects with type 1 diabetes and moderate to severe periodontitis were recruited. Periodontal parameters were measured, and blood samples were obtained to evaluate high-sensitivity C-reactive protein (hs-CRP). Group 1 was treated with scaling, root planning, and systemic administration of doxycycline. Group 2 received only scaling and root planning. Results: Hs-CRP was reduced after periodontal treatment in group 1 (-0.22 mg/l) and 2 (-0.21 mg/l ) but this reduction was not statistically significant, even in the patients with the best response to periodontal treatment. However, significant correlation appeared between hs-CRP and mean probing pocket depth (PPD) (p=0, 01) and mean clinical attachment level (CAL) (p=0,03). Conclusions: Non-surgical periodontal treatment couldn?t reduce hs-CRP values, however, it was found an association between advanced periodontitis and elevated blood hs-CRP levels in patients with type 1 diabetes. It can be speculated that periodontal disease increases production of pro-inflammatory mediators in patients with type 1 diabetes, but other producing sources of these pro-inflammatory substances may exist. es
dc.source Llambés Arenas, Fernando ; Silvestre Donat, Francisco Javier ; Hernández Mijares, Antonio ; Guiha, Rami ; Bautista, Daniel ; Caffesse, Raúl. Efect of periodontal disease and non surgical periodontal treatment on C-reactive protein. Evaluation of type 1 diabetic patients. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 17 4 2012: 16- es
dc.title Efect of periodontal disease and non surgical periodontal treatment on C-reactive protein. Evaluation of type 1 diabetic patients es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.17793 es

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