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Histopathological characterization of the oral lichenoid disease subtypes and the relation with the clinical data

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Histopathological characterization of the oral lichenoid disease subtypes and the relation with the clinical data

dc.contributor.author	Alberdi Navarro, Javier	es
dc.contributor.author	Marichalar Mendia, Xabier	es
dc.contributor.author	Lartitegui Sebastián, María José	es
dc.contributor.author	Gainza Cirauqui, María Luisa	es
dc.contributor.author	Echebarria Goicouria, María Ángeles	es
dc.contributor.author	Aguirre Urízar, José Manuel	es
dc.date.accessioned	2017-07-24T09:29:04Z
dc.date.available	2017-07-24T09:29:04Z
dc.date.issued	2017	es
dc.identifier.uri	http://hdl.handle.net/10550/59845
dc.description.abstract	The aim of the study was to analyze the histopathological characteristics of samples with a diagnosis of oral lichenoid disease (OLD) and their link with the location and the type of clinical lesion, and the clinicopathological subtypes. Retrospective study on 85 consecutive patients diagnosed with OLD (58 women and 27 men, mean age of 57.7 years). Clinical and histopathological characterization of each case (modified WHO criteria). Collection of the clinical and histopathological data of the lesions. Descriptive and comparative statistical analysis of the results. The 78.8% of the cases were considered clinically typical while the 21.2% were considered compatible. Histologically, 52.9% were classified as typical and 47.1% as compatible. Biopsies from ?plaque-like? lesions presented hyperkeratosis (p<0.001) and epithelial dysplasia (p=0.06) more frequently. Furthermore, acute inflammation was more evident in erosive-ulcerative lesions (p=0.001). Differences regarding the location of the biopsy were statistically non-significant. However, 42.9% of the tongue biopsies showed epithelial dysplasia. The histopathological aspect of this disorder is not specific and does not allow us to differentiate between the main subtypes. Therefore, the main reasons to perform a biopsy in this disorder are to define the differential diagnosis and to rule out epithelial dysplasia or a carcinoma. The final histopathological result may be subject to the type of lesion that is biopsied.	es
dc.source	Alberdi Navarro, Javier ; Marichalar Mendia, Xabier ; Lartitegui Sebastián, María José ; Gainza Cirauqui, María Luisa ; Echebarria Goicouria, María Ángeles ; Aguirre Urízar, José Manuel. Histopathological characterization of the oral lichenoid disease subtypes and the relation with the clinical data. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 22 3 2017: 8-	es
dc.title	Histopathological characterization of the oral lichenoid disease subtypes and the relation with the clinical data	es
dc.type	info:eu-repo/semantics/article	en
dc.type	info:eu-repo/semantics/publishedVersion	en
dc.subject.unesco	UNESCO::CIENCIAS MÉDICAS	es
dc.identifier.doi	10.4317/medoral.21730	es