Bisphosphonate treatment and dental implants : a systematic review
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Bisphosphonate treatment and dental implants : a systematic review

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Bisphosphonate treatment and dental implants : a systematic review

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dc.contributor.author de-Freitas, Nayara-Ribeiro es
dc.contributor.author Lima, Lívia-Bonjardim es
dc.contributor.author de-Moura, Marcos-Boaventura es
dc.contributor.author Veloso-Guedes, Cizelene-do-Carmo-Faleiros es
dc.contributor.author Simamoto-Júnior, Paulo-César es
dc.contributor.author de-Magalhães, Denildo es
dc.date.accessioned 2017-07-21T07:53:16Z
dc.date.available 2017-07-21T07:53:16Z
dc.date.issued 2016 es
dc.identifier.uri http://hdl.handle.net/10550/59769
dc.description.abstract To analyze articles that studied patients submitted to diphosphonates therapy and who received dental implants before, during or after bisphosphonate (BP) treatment, compared to healthy patients, analyzing the increase of failure and loss of implants or bisphosphonate related osteonecrosis of the jaw (BRONJ) incidence. The Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) statement was used in this study. The clinical question in ?PICO? format was: In patients under bisphosphonate therapy, do dental implants placement, compared to healthy patients, increase the failure and loss of implants or bisphosphonate related osteonecrosis of the jaw incidence? PubMed/MEDLINE was searched for articles published up until April 15, 2015 using a combination of MeSH terms and their Entry terms. The search resulted in 375 articles. After selection according to the eligibility criteria, 15 studies fulfilled were included (eight retrospective, one prospective and six case series), with a total of 1339 patients analyzed, 3748 implants placed, 152 loss of implants and 78 cases of BRONJ. Due to the lack of randomized clinical trials looking at this theme, further studies with longer follow-up are needed to elucidate the remaining questions. Thus, it is wise to be careful when planning dental implant surgery in patients undergoing bisphosphonate therapy because of the risk of developing BRONJ as well as occurring failure of implant. Moreover, complete systemic condition of the patient must be also taking into considering when such procedures are performed. es
dc.source de-Freitas, Nayara-Ribeiro ; Lima, Lívia-Bonjardim ; de-Moura, Marcos-Boaventura ; Veloso-Guedes, Cizelene-do-Carmo-Faleiros ; Simamoto-Júnior, Paulo-César ; de-Magalhães, Denildo. Bisphosphonate treatment and dental implants : a systematic review. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 21 5 2016: 17- es
dc.title Bisphosphonate treatment and dental implants : a systematic review es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.20920 es

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