Comparison of the analgesic efficacy of oral ketorolac versus intramuscular tramadol after third molar surgery : a parallel, double-blind, randomized, placebo-controlled clinical trial
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Comparison of the analgesic efficacy of oral ketorolac versus intramuscular tramadol after third molar surgery : a parallel, double-blind, randomized, placebo-controlled clinical trial

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Comparison of the analgesic efficacy of oral ketorolac versus intramuscular tramadol after third molar surgery : a parallel, double-blind, randomized, placebo-controlled clinical trial

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dc.contributor.author Espinoza, Mario Alberto Isiordia es
dc.contributor.author Pozos Guillén, Amaury de Jesús es
dc.contributor.author Martínez Rider, Ricardo es
dc.contributor.author Pérez Urizar, José Trinidad es
dc.date.accessioned 2017-07-21T07:53:15Z
dc.date.available 2017-07-21T07:53:15Z
dc.date.issued 2016 es
dc.identifier.uri http://hdl.handle.net/10550/59768
dc.description.abstract Preemptive analgesia is considered an alternative for treating the postsurgical pain of third molar removal. The aim of this study was to evaluate the preemptive analgesic efficacy of oral ketorolac versus intramuscular tramadol after a mandibular third molar surgery. A parallel, double-blind, randomized, placebo-controlled clinical trial was carried out. Thirty patients were randomized into two treatment groups using a series of random numbers: Group A, oral ketorolac 10 mg plus intramuscular placebo (1 mL saline solution); or Group B, oral placebo (similar tablet to oral ketorolac) plus intramuscular tramadol 50 mg diluted in 1 mL saline solution. These treatments were given 30 min before the surgery. We evaluated the time of first analgesic rescue medication, pain intensity, total analgesic consumption and adverse effects. Patients taking oral ketorolac had longer time of analgesic covering and less postoperative pain when compared with patients receiving intramuscular tramadol. According to the VAS and AUC results, this study suggests that 10 mg of oral ketorolac had superior analgesic effect than 50 mg of tramadol when administered before a mandibular third molar surgery. es
dc.source Espinoza, Mario Alberto Isiordia ; Pozos Guillén, Amaury de Jesús ; Martínez Rider, Ricardo ; Pérez Urizar, José Trinidad. Comparison of the analgesic efficacy of oral ketorolac versus intramuscular tramadol after third molar surgery : a parallel, double-blind, randomized, placebo-controlled clinical trial. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 21 5 2016: 12- es
dc.title Comparison of the analgesic efficacy of oral ketorolac versus intramuscular tramadol after third molar surgery : a parallel, double-blind, randomized, placebo-controlled clinical trial es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/medoral.21077 es

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