Double-spanning Plant Viral Movement Protein Integration into the Endoplasmic Reticulum Membrane Is Signal Recognition Particle-dependent, Translocon-mediated, and Concerted
NAGIOS: RODERIC FUNCIONANDO

Double-spanning Plant Viral Movement Protein Integration into the Endoplasmic Reticulum Membrane Is Signal Recognition Particle-dependent, Translocon-mediated, and Concerted

DSpace Repository

Double-spanning Plant Viral Movement Protein Integration into the Endoplasmic Reticulum Membrane Is Signal Recognition Particle-dependent, Translocon-mediated, and Concerted

Show simple item record

dc.contributor.author Saurí Peris, Ana
dc.contributor.author Saksena, Suraj
dc.contributor.author Salgado Benito, Jesús
dc.contributor.author Johnson, Arthur E.
dc.contributor.author Mingarro Muñoz, Ismael
dc.date.accessioned 2016-09-07T18:10:38Z
dc.date.available 2016-09-07T18:10:38Z
dc.date.issued 2005
dc.identifier.uri http://hdl.handle.net/10550/54942
dc.description.abstract The current model for cell-to-cell movement of plant viruses holds that transport requires virus-encoded movement proteins that intimately associate with endoplasmic reticulum membranes. We have examined the early stages of the integration into endoplasmic reticulum membranes of a double-spanning viral movement protein using photocross-linking. We have discovered that this process is cotranslational and proceeds in a signal recognition particle-dependent manner. In addition, nascent chain photocross-linking to Sec61alpha and translocating chain-associated membrane protein reveal that viral membrane protein insertion takes place via the translocon, as with most eukaryotic membrane proteins, but that the two transmembrane segments of the viral protein leave the translocon and enter the lipid bilayer together.
dc.language.iso eng
dc.relation.ispartof Journal of Biological Chemistry, 2005, vol. 280, num. 27, p. 25907-25912
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Saurí Peris, Ana Saksena, Suraj Salgado Benito, Jesús Johnson, Arthur E. Mingarro Muñoz, Ismael 2005 Double-spanning Plant Viral Movement Protein Integration into the Endoplasmic Reticulum Membrane Is Signal Recognition Particle-dependent, Translocon-mediated, and Concerted Journal of Biological Chemistry 280 27 25907 25912
dc.subject Bioquímica
dc.subject Membranes (Biologia)
dc.title Double-spanning Plant Viral Movement Protein Integration into the Endoplasmic Reticulum Membrane Is Signal Recognition Particle-dependent, Translocon-mediated, and Concerted
dc.type info:eu-repo/semantics/article
dc.date.updated 2016-09-07T18:10:38Z
dc.identifier.doi http://dx.doi.org/10.1074/jbc.M412476200
dc.identifier.idgrec 020388

View       (249.2Kb)

This item appears in the following Collection(s)

Show simple item record

Search DSpace

Advanced Search

Browse

Statistics