Premedication with midazolam in intellectually disabled dental patients: intramuscular or oral administration? A retrospective study
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Premedication with midazolam in intellectually disabled dental patients: intramuscular or oral administration? A retrospective study

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Premedication with midazolam in intellectually disabled dental patients: intramuscular or oral administration? A retrospective study

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dc.contributor.author Hanamoto, Hiroshi es
dc.contributor.author Boku, Aiji es
dc.contributor.author Sugimura, Mitsutaka es
dc.contributor.author Oyamaguchi, Aiko es
dc.contributor.author Inoue, Mika es
dc.contributor.author Niwa, Hitoshi es
dc.date.accessioned 2016-07-26T12:01:04Z
dc.date.available 2016-07-26T12:01:04Z
dc.date.issued 2016 es
dc.identifier.uri http://hdl.handle.net/10550/54796
dc.relation es
dc.source Hanamoto, Hiroshi ; Boku, Aiji ; Sugimura, Mitsutaka ; Oyamaguchi, Aiko ; Inoue, Mika ; Niwa, Hitoshi. Premedication with midazolam in intellectually disabled dental patients: intramuscular or oral administration? A retrospective study. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2016, Vol. 21, No. 4: 470- es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Premedication with midazolam in intellectually disabled dental patients: intramuscular or oral administration? A retrospective study es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.description.abstractenglish Background: The use of midazolam for dental care in patients with intellectual disability is poorly documented. The purpose of this study was to determine which method of premedication is more effective for these patients, 0.15 mg/kg of intramuscular midazolam or 0.3 mg/kg of oral midazolam. Material and Methods: This study was designed and implemented as a non-randomized retrospective study. The study population was composed of patients with intellectual disability who required dental treatment under ambulatory general anesthesia from August 2009 through April 2013. Patients were administered 0.15 mg/kg of midazolam intramuscularly (Group IM) or 0.3 mg/kg orally (Group PO). The predictor variable was the method of midazolam administration. The outcome variables measured were Observer’s Assessment of Alertness/ Sedation (OAA/S) Scale scores, the level of cooperation when entering the operation room and for venous cannulation, post-anesthetic agitation and recovery time. Results: Midazolam was administered intramuscularly in 23 patients and orally in 21 patients. More patients were successfully sedated with no resistance behavior during venous cannulation in Group PO than in Group IM ( p =0.034). There were no differences in demographic data and other variables between the groups. Conclusions: The results of this study suggest that oral premedication with 0.3 mg/kg of midazolam is more effective than 0.15 mg/kg of midazolam administered intramuscularly, in terms of patient resistance to venous cannulation. If both oral and intramuscular routes of midazolam are acceptable in intellectually disabled patients, the oral route is recommended. es

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