Histopathological grading systems analysis of oral squamous cell carcinomas of young patients
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Histopathological grading systems analysis of oral squamous cell carcinomas of young patients

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Histopathological grading systems analysis of oral squamous cell carcinomas of young patients

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dc.contributor.author Frare, Juliana-Cristina es
dc.contributor.author Sawazaki-Calone, Iris es
dc.contributor.author Ayroza Rangel, Ana Lúcia Carrinho es
dc.contributor.author Galvão Bueno, Alexandre es
dc.contributor.author Morais, Carlos-Floriano de es
dc.contributor.author Nagai, Hildebrando-Massahiro es
dc.contributor.author Kunz, Reno es
dc.contributor.author Lopes, Márcio Ajudarte es
dc.date.accessioned 2016-07-26T11:58:24Z
dc.date.available 2016-07-26T11:58:24Z
dc.date.issued 2016 es
dc.identifier.uri http://hdl.handle.net/10550/54771
dc.relation es
dc.source Frare, Juliana-Cristina ; Sawazaki-Calone, Iris ; Ayroza Rangel, Ana Lúcia Carrinho ; Galvão Bueno, Alexandre ; Morais, Carlos-Floriano de ; Nagai, Hildebrando-Massahiro ; Kunz, Reno ; Lopes, Márcio Ajudarte. Histopathological grading systems analysis of oral squamous cell carcinomas of young patients. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2016, Vol. 21, No. 3: 285- es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Histopathological grading systems analysis of oral squamous cell carcinomas of young patients es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.description.abstractenglish Background: To analyze the clinicopathological profile of young patients (≤ 40 years) with oral SCC and correlate with a control group (≥ 50 years) by means of histopathological grading systems. Material and Methods: 14 young patients and 14 control patients were selected with similar clinical stage and tumor location. Demographic and clinical data were obtained from patient records and histological sections were evaluated according to four histopathological grading systems. Associations between categories of demographic and clinical data were performed through Chi-square test and Exact Fisher test. The survival analyzes were performed according to the Kaplan-Meier method. Results: The comparison between groups showed a greater association of treatment modalities in younger patients ( p =0.022), they had a higher incidence of local recurrence and regional metastasis ( p =0.018) and lower disease- free survival in 5 years ( p =0.069). There was no difference in 5-year overall survival among the studied groups. There was no difference in histological grading between studied groups according to the four used systems. Conclusions: This study showed that, despite tumors had similar histological grade and more therapeutic modalities were used in the young group, tumors in young patients had a higher incidence of recurrence/metastasis, showing tendency to a more aggressive behavior. es

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