Cocoa Polyphenols and Their Potential Benefits for Human Health
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Cocoa Polyphenols and Their Potential Benefits for Human Health

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Cocoa Polyphenols and Their Potential Benefits for Human Health

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dc.contributor.author Andújar Pérez, Isabel es_ES
dc.contributor.author Recio Iglesias, María del Carmen es_ES
dc.contributor.author Giner Pons, Rosa María es_ES
dc.contributor.author Ríos Cañavate, José Luis es_ES
dc.date.accessioned 2015-06-19T10:17:59Z
dc.date.available 2015-06-19T10:17:59Z
dc.date.issued 2012 es_ES
dc.identifier.uri http://hdl.handle.net/10550/44539
dc.description.abstract This paper compiles the beneficial effects of cocoa polyphenols on human health, especially with regard to cardiovascular and inflammatory diseases, metabolic disorders, and cancer prevention. Their antioxidant properties may be responsible for many of their pharmacological effects, including the inhibition of lipid peroxidation and the protection of LDL-cholesterol against oxidation, and increase resistance to oxidative stress. The phenolics from cocoa also modify the glycemic response and the lipid profile, decreasing platelet function and inflammation along with diastolic and systolic arterial pressures, which, taken together, may reduce the risk of cardiovascular mortality. Cocoa polyphenols can also modulate intestinal inflammation through the reduction of neutrophil infiltration and expression of different transcription factors, which leads to decreases in the production of proinflammatory enzymes and cytokines. The phenolics from cocoa may thus protect against diseases in which oxidative stress is implicated as a causal or contributing factor, such as cancer. They also have antiproliferative, antimutagenic, and chemoprotective effects, in addition to their anticariogenic effects. es_ES
dc.source Oxidative Medicine and Cellular Longevity Vol. 2012 es_ES
dc.title Cocoa Polyphenols and Their Potential Benefits for Human Health es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.identifier.doi 10.1155/2012/906252 es_ES
dc.identifier.idgrec 078592 es_ES

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