Verrucous carcinoma of the oral mucosa: an epidemiological and follow-up study of patients treated with surgery in 5 last years
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Verrucous carcinoma of the oral mucosa: an epidemiological and follow-up study of patients treated with surgery in 5 last years

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Verrucous carcinoma of the oral mucosa: an epidemiological and follow-up study of patients treated with surgery in 5 last years

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dc.contributor.author Candau Álvarez, Alberto es
dc.contributor.author Dean Ferrer, Alicia es
dc.contributor.author Alamillos Granados, Francisco es
dc.contributor.author Heredero Jung, Susana es
dc.contributor.author García García, Blas es
dc.contributor.author Ruiz Masera, J.J. es
dc.contributor.author Arévalo Arévalo, Rafael es
dc.contributor.author Zafra Camacho, F. es
dc.contributor.author Valenzuela Salas, B. es
dc.date.accessioned 2015-01-08T12:34:04Z
dc.date.available 2015-01-08T12:34:04Z
dc.date.issued 2014 es
dc.identifier.uri http://hdl.handle.net/10550/41143
dc.relation http://www.medicinaoral.com/pubmed/medoralv19_i5_p506.pdf es
dc.source Candau Álvarez, Alberto ; Dean Ferrer, Alicia ; Alamillos Granados, Francisco ; Heredero Jung, Susana ; García García, Blas ; Ruiz Masera, J.J. ; Arévalo Arévalo, Rafael ; Zafra Camacho, F. ; Valenzuela Salas, B.. Verrucous carcinoma of the oral mucosa: an epidemiological and follow-up study of patients treated with surgery in 5 last years. En: Medicina oral, patología oral y cirugía bucal. Ed inglesa, 2014, Vol. 19, No. 5: 506-511 es
dc.subject Odontología es
dc.subject Ciencias de la salud es
dc.title Verrucous carcinoma of the oral mucosa: an epidemiological and follow-up study of patients treated with surgery in 5 last years es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.description.abstractenglish Introduction: Oral Verrucous Carcinoma (OVC) is described apart of the Squamous Cell Carcinoma (SCC) due to its specific properties. The objective of our study is to show our series of cases of OVC and to compare with the SCC in terms of clinical manifestations, epidemiology, histopathology, treatment and follow-up. Material and Methods: This is a retrospective study of all the OVC treated in our department between January- 2007 and December-2011. The analyzed variables were sex, age, localization in the oral cavity, histopathology, number of biopsies needed to diagnose OVC, TNM classification, treatment and recurrences during follow-up. Results: Our sample was composed by n=14 patients, 57% female, with a mean age of 69.14 years. The most com - mon localization was buccal mucosa (n=5). Seven patients were diagnosed of OVC with the first biopsy. TNM classification was: pT1: 7 patients, pT2: 3 patients, pT3: 3 patients, pT4: 1 patient. No cervical metastases were observed either in cervical neck dissection or during the follow-up of the patients. The treatment was surgery with clinical resection margins up to 1 cm in all cases, followed by radiotherapy in selected cases. Only n=1 patient (7.69%) presented a recurrence after 34 months of follow-up. The overall survival rate was 92.85%. Conclusions: In our population, OVC represents the 6.16% of all oral cavity and oropharynx cancer, and is more frequent in female patients above 70 years old. It uses to rise over a previous lesion, and usually affects the buccal mucosa. In patients with high suspicious lesions, more than one biopsy may be needed to diagnose OVC. No pa - tient showed cervical dissemination. In our experience, treatment based on local resection, without cervical neck dissection, could be a good option for these patients. es

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