Prebióticos y nucleótidos en alimentación infantil: revisión de la evidencia
NAGIOS: RODERIC FUNCIONANDO

Prebióticos y nucleótidos en alimentación infantil: revisión de la evidencia

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Prebióticos y nucleótidos en alimentación infantil: revisión de la evidencia

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dc.contributor.author Cilla Tatay, Antonio
dc.contributor.author Lacomba Perales, Ramón
dc.contributor.author García Llatas, Guadalupe
dc.contributor.author Alegría Torán, Amparo Asunción
dc.date.accessioned 2014-02-26T15:08:45Z
dc.date.available 2014-02-26T15:08:45Z
dc.date.issued 2012
dc.identifier.uri http://dx.doi.org/10.3305/nh.2012.27.4.5811
dc.identifier.uri http://hdl.handle.net/10550/33382
dc.description.abstract Introduction: Most of the initiation and maintenance pediatric formulas commercialized in Spain contain prebiotics and/or nucleotides aiming at achieving beneficial effects on prevention of different pathologies and immune protection, similar to human breast milk. However, according to the current legislation, its inclusion is optional since sufficient scientific evidences supporting its mandatory inclusion is lacking. Objective: To systematically review the scientific evidence from randomized clinical studies with a control group allowing determining the beneficial role for infant health derived from the inclusion of prebiotics and/or nucleotides in pediatric formulas. Methodology: We looked for and selected both original papers and reviews in Spanish and English language of placebo controlled randomized clinical studies published in the databases MEDLINE/PubMed, Scielo, Science Direct, and Scopus, until October of 2011. Results: We found 43 randomized clinical trials meeting the inclusion criteria. Conclusions: More long-term randomized studies with higher number of patients, and standardized supplemental amounts and experimental conditions are needed to establish healthy statements with stronger scientific support regarding the addition of a mixture of prebiotics (GOS/FOS) and/or nucleotides in pediatric formulas. The current trend to include them in pediatric formulas may be justified based on the currently available evidence, as well as their safety and their presence in human breast milk.
dc.relation.ispartof Nutricion Hospitalaria, 2012, vol. 27, p. 1037-1048
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Cilla Tatay, Antonio Lacomba Perales, Ramón García Llatas, Guadalupe Alegría Torán, Amparo Asunción 2012 Prebióticos y nucleótidos en alimentación infantil; revisión de la evidencia Nutricion Hospitalaria 27 1037 1048
dc.subject Infants Alimentació
dc.title Prebióticos y nucleótidos en alimentación infantil: revisión de la evidencia
dc.type info:eu-repo/semantics/article
dc.date.updated 2014-02-26T15:08:45Z
dc.identifier.doi http://dx.doi.org/10.3305/nh.2012.27.4.5811
dc.identifier.idgrec 080152

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