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Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma.

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Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma.

dc.contributor.author	Frasquet, M.
dc.contributor.author	Bataller, L.
dc.contributor.author	Torres-Vega, E.
dc.contributor.author	Durán Moreno, María
dc.contributor.author	García Verdugo, José Manuel
dc.contributor.author	Sevilla, T.
dc.contributor.author	Rivas, Salvador
dc.contributor.author	Pérez-Miralles, F.
dc.contributor.author	Simó-Castelló, M.
dc.contributor.author	Casanova, B.
dc.date.accessioned	2014-01-20T08:50:11Z
dc.date.available	2014-01-20T08:50:11Z
dc.date.issued	2013
dc.identifier.uri	http://dx.doi.org/10.1016/j.jneuroim.2013.07.003
dc.identifier.uri	http://hdl.handle.net/10550/32388
dc.description.abstract	Paraneoplastic myelitis is a rare inflammatory disorder most frequently associated with solid tumors or lymphoproliferative disorders. Patients often harbor onconeuronal antibodies and their prognosis is usually poor. Here we report a 42-year old woman with longitudinally extensive transverse myelitis and aquaporin-4 (AQP4) antibodies that led to the diagnosis of ovarian teratoma. After tumor removal and immune therapy (including corticosteroids, plasma exchange, intravenous immunoglobulins and rituximab) the patient progressively improved achieving complete recovery. Histological study of the teratoma demonstrated neural tissue containing AQP4 expressing cells and intense inflammatory infiltrates, providing evidence for a possible paraneoplastic link between both disorders.
dc.relation.ispartof	Journal of Neuroimmunology, 2013, vol. 263, num. 1-2, p. 145-147
dc.source	Frasquet, M. Bataller, L. Torres-Vega, E. Durán Moreno, María García Verdugo, José Manuel Sevilla, T. Rivas, Salvador Pérez-Miralles, F. Simó-Castelló, M. Casanova, B. 2013 Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma. Journal of Neuroimmunology 263 1-2 145 147
dc.subject	Neurociències
dc.subject	Sistema nerviós Malalties
dc.title	Longitudinally extensive transverse myelitis with AQP4 antibodies revealing ovarian teratoma.
dc.type	journal article	es_ES
dc.date.updated	2014-01-20T08:50:11Z
dc.identifier.doi	http://dx.doi.org/10.1016/j.jneuroim.2013.07.003
dc.identifier.idgrec	093139
dc.rights.accessRights	open access	es_ES