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Genomics and the gene transcription kinetics in yeast.

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Genomics and the gene transcription kinetics in yeast.

dc.contributor.author	Pérez Ortín, José Enrique
dc.contributor.author	Alepuz Martínez, Paula
dc.contributor.author	Moreno Mariño, Joaquín
dc.date.accessioned	2013-12-16T10:23:12Z
dc.date.available	2013-12-16T10:23:12Z
dc.date.issued	2007
dc.identifier.uri	http://dx.doi.org/10.1016/j.tig.2007.03.006
dc.identifier.uri	http://hdl.handle.net/10550/32118
dc.description.abstract	As an adaptive response to new conditions, mRNA concentrations in eukaryotes are readjusted after any environmental change. Although mRNA concentrations can be modified by altering synthesis and/or degradation rates, the rapidity of the transition to a new concentration depends on the regulation of mRNA stability. There are several plausible transcriptional strategies following environmental change, reflecting different degrees of compromise between speed of response and cost of synthesis. The recent development of genomic techniques now enables researchers to determine simultaneously (either directly or indirectly) the transcription rates and mRNA half-lifes, together with mRNA concentrations, corresponding to all yeast genes. Such experiments could provide a new picture of the transcriptional response, by enabling us to characterize the kinetic strategies that are used by different genes under given environmental conditions.
dc.relation.ispartof	Trends in Genetics, 2007, vol. 23, num. 5, p. 250-257
dc.rights.uri	info:eu-repo/semantics/openAccess
dc.source	Pérez Ortín, José Enrique Alepuz Martínez, Paula Moreno Mariño, Joaquín 2007 Genomics and the gene transcription kinetics in yeast. Trends in Genetics 23 5 250 257
dc.subject	Saccharomyces
dc.subject	Genòmica
dc.subject	Transcripció genètica
dc.title	Genomics and the gene transcription kinetics in yeast.
dc.type	info:eu-repo/semantics/article
dc.date.updated	2013-12-16T10:23:12Z
dc.identifier.doi	http://dx.doi.org/10.1016/j.tig.2007.03.006
dc.identifier.idgrec	033667