Genomics of mRNA turnover
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Genomics of mRNA turnover

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Genomics of mRNA turnover

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dc.contributor.author Pérez Ortín, José Enrique
dc.date.accessioned 2013-12-09T09:42:22Z
dc.date.available 2013-12-09T09:42:22Z
dc.date.issued 2007
dc.identifier.uri http://dx.doi.org/10.1093/bfgp/elm029
dc.identifier.uri http://hdl.handle.net/10550/32062
dc.description.abstract Most studies on eukaryotic gene regulation have focused on mature mRNA levels. Nevertheless, the steady-state mRNA level is the result of two opposing biological processes: transcription and degradation, both of which can be important points to regulate gene expression. It is now possible to determine the transcription and degradation rates (TR and DR), as well as the mRNA amount, for each gene using DNA chip technologies. In this way, each individual contribution to gene expression can be analysed. This review will deal with the techniques used for the genomic evaluation of TR and DR developed for the yeast Saccharomyces cerevisiae. They will be described in detail and their potential drawbacks discussed. I will also discuss the integration of the data obtained to fully analyse the expression strategies used by yeast and other eukaryotic cells.
dc.relation.ispartof Briefings in Functional Genomics & Proteomics, 2007, vol. 6, num. 4, p. 282-291
dc.rights.uri info:eu-repo/semantics/openAccess
dc.source Pérez Ortín, José Enrique 2007 Genomics of mRNA turnover Briefings in Functional Genomics & Proteomics 6 4 282 291
dc.subject Genòmica
dc.subject Saccharomyces cerevisiae
dc.subject RNA
dc.subject ADN
dc.subject Transcripció genètica
dc.title Genomics of mRNA turnover
dc.type info:eu-repo/semantics/article
dc.date.updated 2013-12-09T09:42:22Z
dc.identifier.doi http://dx.doi.org/10.1093/bfgp/elm029
dc.identifier.idgrec 041243

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