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mRNAstab : a web application for mRNA stability analysis

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mRNAstab : a web application for mRNA stability analysis

dc.contributor.author	Alic, Andrei
dc.contributor.author	Pérez Ortín, José Enrique
dc.contributor.author	Moreno Mariño, Joaquín
dc.contributor.author	Arnau Llombart, Vicente
dc.date.accessioned	2013-12-04T08:45:32Z
dc.date.available	2014-03-15T08:45:32Z
dc.date.issued	2013
dc.identifier.uri	http://dx.doi.org/10.1093/bioinformatics/btt04
dc.identifier.uri	http://hdl.handle.net/10550/31698
dc.description.abstract	Eukaryotic gene expression is regulated both at the transcription and the mRNA degradation levels. The implementation of functional genomics methods that allow the simultaneous measurement of transcription (TR) and degradation (DR) rates for thousands of mRNAs is a huge improvement in this field. One of the best established methods for mRNA stability determination is genomic run-on (GRO). It allows the measurement of DR, TR and mRNA levels during cell dynamic responses. Here, we offer a software package that provides improved algorithms for determination of mRNA stability during dynamic GRO experiments.
dc.relation.ispartof	Bioinformatics, 2013, vol. 29, p. 813-814
dc.source	Alic, Andrei Pérez Ortín, José Enrique Moreno Mariño, Joaquín Arnau llombart, Vicente 2013 mRNAstab. A web application for mRNA stability analysis. Bioinformatics 29 813 814
dc.subject	Expressió genètica
dc.subject	Genòmica
dc.subject	RNA
dc.title	mRNAstab : a web application for mRNA stability analysis
dc.type	journal article	es_ES
dc.date.updated	2013-12-04T08:45:32Z
dc.identifier.doi	http://dx.doi.org/10.1093/bioinformatics/btt04
dc.identifier.idgrec	084574
dc.rights.accessRights	open access	es_ES