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mRNAstab : a web application for mRNA stability analysis

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	Alic, Andrei; Pérez Ortín, José Enrique Perfil; Moreno Mariño, Joaquín; Arnau Llombart, Vicente
	This document is a artículoDate2013
	Este documento está disponible también en : http://dx.doi.org/10.1093/bioinformatics/btt04
	Este documento está disponible también en : http://hdl.handle.net/10550/31698
	Eukaryotic gene expression is regulated both at the transcription and the mRNA degradation levels. The implementation of functional genomics methods that allow the simultaneous measurement of transcription (TR) and degradation (DR) rates for thousands of mRNAs is a huge improvement in this field. One of the best established methods for mRNA stability determination is genomic run-on (GRO). It allows the measurement of DR, TR and mRNA levels during cell dynamic responses. Here, we offer a software package that provides improved algorithms for determination of mRNA stability during dynamic GRO experiments.
	Alic, Andrei Pérez Ortín, José Enrique Moreno Mariño, Joaquín Arnau llombart, Vicente 2013 mRNAstab. A web application for mRNA stability analysis. Bioinformatics 29 813 814
	http://dx.doi.org/10.1093/bioinformatics/btt04