Influence of Concurrent Obesity and Low Birth Weight on Blood Pressure Phenotype in Youth
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Influence of Concurrent Obesity and Low Birth Weight on Blood Pressure Phenotype in Youth

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Influence of Concurrent Obesity and Low Birth Weight on Blood Pressure Phenotype in Youth

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dc.contributor.author Lurbe i Ferrer, Empar
dc.contributor.author Carvajal Roca, María Eva
dc.contributor.author Torró Doménech, María Isabel
dc.contributor.author Aguilar, Francisco
dc.contributor.author Alvarez, Julio
dc.contributor.author Redón i Más, Josep
dc.date.accessioned 2010-04-23T11:49:17Z
dc.date.available 2010-04-23T11:49:17Z
dc.date.issued 2009
dc.identifier.uri http://hdl.handle.net/10550/2268
dc.language.iso en en
dc.relation http://hyper.ahajournals.org/cgi/reprint/53/6/912 en
dc.source LURBER, Empar; CARVAJAL, Eva; TORRO, Isabel; AGUILAR, Francisco; ALVAREZ, Julio; REDON, Josep. Influence of Concurrent Obesity and Low Birth Weight on Blood Pressure Phenotype in Youth. En: Hipertension, vol. 53, p. 912-917 en
dc.subject Peso de nacimiento; Obesidad; Adolescencia; Presión sanguínea en
dc.title Influence of Concurrent Obesity and Low Birth Weight on Blood Pressure Phenotype in Youth en
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS en
dc.identifier.doi 10.1161/HYPERTENSIONAHA.109.129155 en
dc.description.abstractenglish The aim of this study was to assess the impact of obesity and low birth weight on both office and ambulatory blood pressure (BP) values, as well as on aortic-derived parameters in youths. A total of 422 white youths, from 10 to 18 years of age, were included. Subjects were divided into 4 groups according to the presence (234; 55%) or the absence (188; 45%) of obesity and according to low (114; 27%) or normal (308; 73%, birth weight. Spacelabs 90207 was used to measure ambulatory BP during a 24-hour period. SphygmoCor radial/aortic transform software was used to estimate aortic pressure waveform. Office, 24-hour, daytime, and nighttime systolic BP values were significantly higher in those subjects with low birth weight who became obese. The lowest BP values were present in nonobese subjects in the absence of low birth weight. In the middle, with similar BP values, were nonobese subjects with low birth weight and obese subjects in the absence of low birth weight. No interaction existed between obesity and low birth weight in the office (P 0.165) or ambulatory (P 0.603) systolic BP values. Augmentation index, an estimate of the pulse wave reflection, was significantly higher in the nonobese low birth weight group when compared with the other groups after controlling for height, heart rate, and diastolic BP. A significant interaction between low birth weight and obesity (P 0.005) existed. In conclusion, although the low birth weight children who become obese have the highest systolic BP values, the presence of obesity blunts the increment of the reflecting wave observed in low birth weight subjects. en
dc.description.private -Empar.Lurbe@uv.es -Josep.Redon@uv.es en

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