Effectiveness of different vaccine formulations against vibriosis caused by Vibrio vulnificus serovar E (biotype 2) in European eels Anguilla anguilla
NAGIOS: RODERIC FUNCIONANDO

Effectiveness of different vaccine formulations against vibriosis caused by Vibrio vulnificus serovar E (biotype 2) in European eels Anguilla anguilla

DSpace Repository

Effectiveness of different vaccine formulations against vibriosis caused by Vibrio vulnificus serovar E (biotype 2) in European eels Anguilla anguilla

Show simple item record

dc.contributor.author Collado Nieto, Rosa María
dc.contributor.author Fouz Rodríguez, Belén
dc.contributor.author Sanjuán Caro, Eva
dc.contributor.author Amaro González, Carmen
dc.date.accessioned 2011-08-19T09:12:39Z
dc.date.available 2011-08-19T09:12:39Z
dc.date.issued 2000
dc.identifier.uri http://hdl.handle.net/10550/20047
dc.description.abstract Vibriosis due to Vibrio vulnificus serovar E (biotype 2) is one of the main causes of mortality in European eels cultured in Europe. The main objective of this study was to develop a vaccine and a vaccination procedure against this pathogen. With this aim, we tested several vaccine formulations (inactivated whole-cells with and without toxoids‹inactivated extracellular products‹from capsulated and uncapsulated strains, attenuated live vaccines and purified lipopolysaccharide [LPS]) on eels maintained under controlled laboratory conditions using different delivery routes (injection and immersion). To study the immune response we estimated antibody titers and bactericidal/bacteriostatic activity in mucus and serum. To evaluate protection, we calculated the relative percent survival (RPS) after intraperitoneal (i.p.) injection and bath challenge of the pathogen. The overall results indicate that: (1) capsular antigens seem to be essential for protective immunization; (2) vaccines confer the highest protection when administered by i.p. injection; (3) booster is needed to achieve good protection by immersion; (4) enriching the vaccine with toxoids enhances protection to optimal levels (RPS values around 70 to 100%, depending on the delivery route); and (5) the protective effect in serum and mucus depends on the route of administration and seems to be related to the production of specific antibodies. en
dc.language.iso en en
dc.relation http://www.int-res.com/articles/dao/43/d043p091.pdf en
dc.source COLLADO, Rosa ; Fouz Rodriguez, Belen ; Sanjuan Caro, Eva ; Amaro Gonzalez, Carmen, 2000, Effectiveness of different vaccine formulations against vibriosis caused by Vibrio vulnificus serovar E (biotype 2) in European eels Anguilla anguilla, Diseases of Aquatic Organisms, vol. 43, no. 2, p. 91-101 en
dc.subject Vibrio vulnificus serovar E ; Vibrio vulnificus biotype 2 ; Eel vaccines ; Vibrio vaccines ; Vaccination by injection ; Vaccination by prolonged immersion en
dc.title Effectiveness of different vaccine formulations against vibriosis caused by Vibrio vulnificus serovar E (biotype 2) in European eels Anguilla anguilla en
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS DE LA VIDA en
dc.subject.unesco UNESCO::CIENCIAS DE LA VIDA::Biología animal (Zoología) en
dc.identifier.doi http://dx.doi.org/10.3354/dao043091 en
dc.description.private Fouz Rodriguez, Belen, Belen.Fouz@uv.es ; Sanjuan Caro, Eva, Eva.Sanjuan@uv.es ; Amaro Gonzalez, Carmen, Carmen.Amaro@uv.es en

View       (164.6Kb)

This item appears in the following Collection(s)

Show simple item record

Search DSpace

Advanced Search

Browse

Statistics