dc.contributor.author |
Moreno Gimeno, Inmaculada |
|
dc.contributor.author |
Tutrone, Nuncia |
|
dc.contributor.author |
Sentandreu Ramon, Rafael |
|
dc.contributor.author |
Valentín Gómez, Eulogio |
|
dc.date.accessioned |
2010-06-14T08:01:16Z |
|
dc.date.available |
2010-06-14T08:01:16Z |
|
dc.date.issued |
2008 |
|
dc.identifier.uri |
http://hdl.handle.net/10550/12936 |
|
dc.description.abstract |
Although the cell wall is very important in yeasts, relatively little is known about the relationship between its structure and function. In Saccharomyces cerevisiae, a family of 55 transcription factor proteins unique to fungi, so-called zinc cluster proteins, has been described. Of these, Rds2 has been identified as an activator/inhibitor of gluconeogenesis. However, previous studies have pointed out additional roles for this protein, specifically, in the modulation of cell-wall architecture and drug sensitivity. In this work, evidence regarding the role of Rds2 as a regulator of cell-wall architecture and composition is presented based on phenotypical analysis of the cell walls prepared from a S. cerevisiae Rds2 mutant strain. Analyses of the sensitivity of this rds2Δ mutant to different drugs and to osmotic stress showed that Rds2 is indeed involved in the drug-sensitivity response and plays a role in determining osmotic sensitivity. |
en |
dc.language.iso |
en |
en |
dc.relation |
http://www.im.microbios.org/1101/110157.pdf |
en |
dc.source |
MORENO GIMENO, Inmaculada ; Tutrone, Nuncia ; Sentandreu Ramon, Rafael ; Valentin Gomez, Eulogio, 2008, Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture, International Microbiology, vol. 11, no. 1, p.57-63 |
en |
dc.subject |
Saccharomyces cerevisiae ; Transcription factors ; Gene RDS2 ; Cell wall |
en |
dc.title |
Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture |
en |
dc.type |
info:eu-repo/semantics/article |
en |
dc.type |
info:eu-repo/semantics/publishedVersion |
en |
dc.subject.unesco |
UNESCO::CIENCIAS DE LA VIDA::Microbiología |
en |
dc.subject.unesco |
UNESCO::CIENCIAS DE LA VIDA::Microbiología |
en |
dc.identifier.doi |
10.2436/20.1501.01.45 |
en |
dc.description.private |
Moreno Gimeno, Inmaculada, Inmaculada.Moreno@uv.es ;
Sentandreu Ramon, Rafael, Rafael.Sentandreu@uv.es ;
Valentin Gomez, Eulogio, Eulogio.Valentin@uv.es |
en |
dc.identifier.idgrec |
043376 |
en |