NAGIOS: RODERIC FUNCIONANDO

Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture

DSpace Repository

Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture

dc.contributor.author	Moreno Gimeno, Inmaculada
dc.contributor.author	Tutrone, Nuncia
dc.contributor.author	Sentandreu Ramon, Rafael
dc.contributor.author	Valentín Gómez, Eulogio
dc.date.accessioned	2010-06-14T08:01:16Z
dc.date.available	2010-06-14T08:01:16Z
dc.date.issued	2008
dc.identifier.uri	http://hdl.handle.net/10550/12936
dc.description.abstract	Although the cell wall is very important in yeasts, relatively little is known about the relationship between its structure and function. In Saccharomyces cerevisiae, a family of 55 transcription factor proteins unique to fungi, so-called zinc cluster proteins, has been described. Of these, Rds2 has been identified as an activator/inhibitor of gluconeogenesis. However, previous studies have pointed out additional roles for this protein, specifically, in the modulation of cell-wall architecture and drug sensitivity. In this work, evidence regarding the role of Rds2 as a regulator of cell-wall architecture and composition is presented based on phenotypical analysis of the cell walls prepared from a S. cerevisiae Rds2 mutant strain. Analyses of the sensitivity of this rds2Δ mutant to different drugs and to osmotic stress showed that Rds2 is indeed involved in the drug-sensitivity response and plays a role in determining osmotic sensitivity.	en
dc.language.iso	en	en
dc.relation	http://www.im.microbios.org/1101/110157.pdf	en
dc.source	MORENO GIMENO, Inmaculada ; Tutrone, Nuncia ; Sentandreu Ramon, Rafael ; Valentin Gomez, Eulogio, 2008, Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture, International Microbiology, vol. 11, no. 1, p.57-63	en
dc.subject	Saccharomyces cerevisiae ; Transcription factors ; Gene RDS2 ; Cell wall	en
dc.title	Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture	en
dc.type	info:eu-repo/semantics/article	en
dc.type	info:eu-repo/semantics/publishedVersion	en
dc.subject.unesco	UNESCO::CIENCIAS DE LA VIDA::Microbiología	en
dc.subject.unesco	UNESCO::CIENCIAS DE LA VIDA::Microbiología	en
dc.identifier.doi	10.2436/20.1501.01.45	en
dc.description.private	Moreno Gimeno, Inmaculada, Inmaculada.Moreno@uv.es ; Sentandreu Ramon, Rafael, Rafael.Sentandreu@uv.es ; Valentin Gomez, Eulogio, Eulogio.Valentin@uv.es	en
dc.identifier.idgrec	043376	en