Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture
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Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture

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Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture

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dc.contributor.author Moreno Gimeno, Inmaculada
dc.contributor.author Tutrone, Nuncia
dc.contributor.author Sentandreu Ramon, Rafael
dc.contributor.author Valentín Gómez, Eulogio
dc.date.accessioned 2010-06-14T08:01:16Z
dc.date.available 2010-06-14T08:01:16Z
dc.date.issued 2008
dc.identifier.uri http://hdl.handle.net/10550/12936
dc.description.abstract Although the cell wall is very important in yeasts, relatively little is known about the relationship between its structure and function. In Saccharomyces cerevisiae, a family of 55 transcription factor proteins unique to fungi, so-called zinc cluster proteins, has been described. Of these, Rds2 has been identified as an activator/inhibitor of gluconeogenesis. However, previous studies have pointed out additional roles for this protein, specifically, in the modulation of cell-wall architecture and drug sensitivity. In this work, evidence regarding the role of Rds2 as a regulator of cell-wall architecture and composition is presented based on phenotypical analysis of the cell walls prepared from a S. cerevisiae Rds2 mutant strain. Analyses of the sensitivity of this rds2Δ mutant to different drugs and to osmotic stress showed that Rds2 is indeed involved in the drug-sensitivity response and plays a role in determining osmotic sensitivity. en
dc.language.iso en en
dc.relation http://www.im.microbios.org/1101/110157.pdf en
dc.source MORENO GIMENO, Inmaculada ; Tutrone, Nuncia ; Sentandreu Ramon, Rafael ; Valentin Gomez, Eulogio, 2008, Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture, International Microbiology, vol. 11, no. 1, p.57-63 en
dc.subject Saccharomyces cerevisiae ; Transcription factors ; Gene RDS2 ; Cell wall en
dc.title Saccharomyces cerevisiae Rds2 transcription factor involvement in cell wall composition and architecture en
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS DE LA VIDA::Microbiología en
dc.subject.unesco UNESCO::CIENCIAS DE LA VIDA::Microbiología en
dc.identifier.doi 10.2436/20.1501.01.45 en
dc.description.private Moreno Gimeno, Inmaculada, Inmaculada.Moreno@uv.es ; Sentandreu Ramon, Rafael, Rafael.Sentandreu@uv.es ; Valentin Gomez, Eulogio, Eulogio.Valentin@uv.es en
dc.identifier.idgrec 043376 en

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