NAGIOS: RODERIC FUNCIONANDO

Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers

DSpace Repository

Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers

dc.contributor.author	García-Fortanet, Jorge
dc.contributor.author	Murga, Juan
dc.contributor.author	Carda, Miguel
dc.contributor.author	Marco Ventura, Juan Alberto
dc.date.accessioned	2010-06-08T10:26:28Z
dc.date.available	2010-06-08T10:26:28Z
dc.date.issued	2005
dc.identifier.uri	http://hdl.handle.net/10550/12896
dc.description.abstract	A stereoselective synthesis is described of the structure published for the naturally occurring synargentolide A, an α,β-unsaturated lactone. The key steps of the synthesis were a Brown´s asymmetric allylation and a ring closing metathesis. The spectroscopic data of the synthetic product were very close to those of the natural product but did not exactly match them. An epimer of the published structure was then synthesized according to a similar strategy. Again, the data of the synthetic product did not match those reported for the natural product. It is thus likely that the actual structure of synargentolide A differs from the published one in more than mere stereochemical aspects.	en
dc.language.iso	en	en
dc.relation	http://www.arkat-usa.org/get-file/19597/	en
dc.source	GARCÍA-FORTANET, Jorge ; Murga, Juan ; Carda, Miguel ; Marco Ventura, Juan Alberto, 2005, Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers, Arkivoc, vol. 2005, no. IX, p. 175-188	en
dc.subject	Synargentolide A ; Ring-closing metathesis ; Asymmetric allylboration ; Asymmetric dihydroxylation	en
dc.title	Stereoselective synthesis of the published structure of synargentolide A and of one of its stereoisomers	en
dc.type	journal article	es_ES
dc.subject.unesco	UNESCO::QUÍMICA	en
dc.subject.unesco	UNESCO::QUÍMICA::Química orgánica	en
dc.description.private	Marco Ventura, Juan Alberto, alberto.marco@uv.es	en
dc.identifier.idgrec	020768	en
dc.type.hasVersion	VoR	es_ES