The cell wall structure: developments in diagnosis and treatment of candidiasis
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The cell wall structure: developments in diagnosis and treatment of candidiasis

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The cell wall structure: developments in diagnosis and treatment of candidiasis

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dc.contributor.author Marcilla Diaz, Antonio
dc.contributor.author Valentín Gómez, Eulogio
dc.contributor.author Sentandreu Ramon, Rafael
dc.date.accessioned 2010-06-03T07:43:03Z
dc.date.available 2010-06-03T07:43:03Z
dc.date.issued 1998
dc.identifier.uri http://hdl.handle.net/10550/12854
dc.description.abstract Candidiasis are among the fungal infections the most difficult to diagnose and treat. Research focused on specific fungal components which are absent in the host, such as the cell wall has lead to a better understanding of Candida albicans pathogenicity and clinical impact. The cell wall is responsible for antigenic expression and primary interaction with the host. It is composed mainly of b-glucans, chitin and mannoproteins, which account for the rigidity of the wall and for the fungal morphology. Of these components, mannoproteins might carry a “morphogenetic code” which might modulate the molecular architecture of the cell wall. The features of specific cell wall proteins as part of building blocks to form this structure is revised, and the usefulness of monoclonal antibodies obtained against cell wall components to study those processes, together with their clinical applicability, is discussed. en
dc.language.iso en en
dc.relation http://www.im.microbios.org/02june98/05%20Marcilla.pdf en
dc.source Marcilla Diaz, Antonio; Valentin Gomez, Eulogio; Sentandreu Ramon, Rafael. The cell wall structure: developments in diagnosis and treatment of candidiasis. En International Microbiology, 1998, 1:107–116 en
dc.subject Candidiasis; Cell wall; Mannoproteins; Monoclonal antibodies en
dc.title The cell wall structure: developments in diagnosis and treatment of candidiasis en
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS DE LA VIDA::Microbiología en
dc.description.private marcilla@uv.es; valentin@uv.es; sentandr@uv.es en

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