Copper-catalysed enantioselective Michael addition of malonic esters to β-trifluoromethyl-α,β-unsaturated imines
NAGIOS: RODERIC FUNCIONANDO

Copper-catalysed enantioselective Michael addition of malonic esters to β-trifluoromethyl-α,β-unsaturated imines

DSpace Repository

Copper-catalysed enantioselective Michael addition of malonic esters to β-trifluoromethyl-α,β-unsaturated imines

Show full item record

View       (516.3Kb)

Exportar a Refworks
    
Espinosa López, Miguel; Herrera, Jorge; Blay Llinares, Gonzalo Perfil; Cardona Prósper, María Luz; Muñoz, M. Carmen; Pedro, José Ramón
This document is a artículoDate2017
Copper triflate-BOX complexes catalyse the enantioselective conjugate addition of methyl malonate to β-trifluoromethyl-α,β-unsaturated imines to give the corresponding enamines bearing a trifluoromethylated stereogenic centre with good yields, and diastereo- and enantioselectivities. The usefulness of the method has been shown with the synthesis of optically active β-trifluoromethyl δ-amino esters and optically active trifluoromethylpiperidones.

    Espinosa López, Miguel Herrera, Jorge Blay Llinares, Gonzalo Cardona Prósper, María Luz Muñoz, M. Carmen Pedro, José Ramón 2017 Copper-catalysed enantioselective Michael addition of malonic esters to β-trifluoromethyl-α,β-unsaturated imines Organic & Biomolecular Chemistry 15 3849 3853
https://doi.org/10.1039/C7OB00595D

This item appears in the following Collection(s)

Show full item record

Search DSpace

Advanced Search

Browse

Statistics