Oral paracoccidioidomycosis in a non-endemic region from Brazil: a short case series
NAGIOS: RODERIC FUNCIONANDO

Oral paracoccidioidomycosis in a non-endemic region from Brazil: a short case series

DSpace Repository

Oral paracoccidioidomycosis in a non-endemic region from Brazil: a short case series

Show simple item record

dc.contributor.author Souza, Reydson-Alcides-de Lima es
dc.contributor.author Bonan, Paulo Rogério Ferreti es
dc.contributor.author Pinto, Mariana-Bitu-Ramos es
dc.contributor.author Prado, José-Divaldo es
dc.contributor.author Castro, Jurema Freire Lisboa de es
dc.contributor.author Carvalho, Elaine Judite de Amorim es
dc.contributor.author Perez, Danyel Elias da Cruz es
dc.date.accessioned 2019-11-22T12:22:21Z
dc.date.available 2019-11-22T12:22:21Z
dc.date.issued 2019 es
dc.identifier.uri https://hdl.handle.net/10550/72334
dc.description.abstract Although the paracoccidioidomycosis (PCM) is endemic in Brazil, the occurrence in most states from the North and Northeastern Brazil is very unusual. The aim of this study was to evaluate the clinicopathologic features of a case series of oral PCM in a non-endemic region from Brazil (Northeastern region), discussing the clinical and histopathological differential diagnoses of the oral manifestations of the disease. Between 2000 and 2017, all cases of oral PCM were retrieved from the Oral Pathology Laboratory, Universidade Federal de Pernambuco, located at Northeastern Brazil. Clinical data, such as age, gender, origin, occupation, site, symptoms, time of complaints, clinical presentation, number of lesions, and clinical hypotheses of diagnosis, were collected from the clinical charts. All cases were histologically reviewed in hematoxylin-eosin and Gomori-Grocott staining. Six cases were identified. All patients were male, with a mean age of 53.8 years (ranging from 40 to 73 years). Four cases appeared as multiple ulcers and two presented single lesions (buccal mucosa and hard palate). Clinically, in five cases, squamous cell carcinoma was considered in the differential diagnosis. The common histopathological features consisted of hyperplastic epithelium, intraepithelial microabscesses, and formation of granulomatous chronic inflammatory reaction in a fibrous connective tissue with severe chronic inflammatory reaction. Yeasts were observed either inside of multinucleated giant cells or extracellularly. Although rare in non-endemic regions, oral PCM should be considered in the differential diagnosis of oral chronic ulcers, mainly those multiple. es
dc.source Souza, Reydson-Alcides-de Lima ; Bonan, Paulo Rogério Ferreti ; Pinto, Mariana-Bitu-Ramos ; Prado, José-Divaldo ; Castro, Jurema Freire Lisboa de ; Carvalho, Elaine Judite de Amorim ; Perez, Danyel Elias da Cruz. Oral paracoccidioidomycosis in a non-endemic region from Brazil : a short case series. En: Journal of Clinical and Experimental Dentistry, 11 10 2019: 865-870 es
dc.title Oral paracoccidioidomycosis in a non-endemic region from Brazil: a short case series es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.56199 es

View       (1.969Mb)

This item appears in the following Collection(s)

Show simple item record

Search DSpace

Advanced Search

Browse

Statistics