Extensive osteonecrosis of the maxilla caused by bisphosphonates : report of a rare case
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Extensive osteonecrosis of the maxilla caused by bisphosphonates : report of a rare case

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Extensive osteonecrosis of the maxilla caused by bisphosphonates : report of a rare case

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dc.contributor.author Santos, Murilo es
dc.contributor.author Silveira, Karoline es
dc.contributor.author Souza, Natália es
dc.contributor.author Costa, Davi es
dc.contributor.author Inaoka, Sirius es
dc.date.accessioned 2019-04-01T12:02:10Z
dc.date.available 2019-04-01T12:02:10Z
dc.date.issued 2019 es
dc.identifier.uri http://hdl.handle.net/10550/69674
dc.description.abstract Bisphosphonates are drugs indicated for the treatment of bone metabolic diseases or malignant hypercalcemia. They are generally well-tolerated drugs, however, recent reports have described osteonecrosis of the jaw bones as a potentially serious complication related to the long-term use of these drugs. We report a case of severe osteonecrosis in a 52-years-old white woman that was taking bisphosphonates (zoledronic acid and alendronate) for the management of osteoporosis. Following a long exposure to these drugs and after being subjected to multiples exodontias, developed bisphosphonate-related osteonecrosis of the jaw compromising the whole maxilla and that extended toward the base of skull. Due to the extent of osteonecrosis, total maxillectomy and removal of all adjacent necrotic bone were planned guided by ultraviolet light. fluorescence. This case illustrates that if not treated correctly, bisphosphonate-related osteonecrosis of the jaw may cause significant morbidity, affect the quality of life and can eventually produce significant morbidity with the dissemination to noble structures and potentially causing life-threatening complications. es
dc.source Santos, Murilo ; Silveira, Karoline ; Souza, Natália ; Costa, Davi ; Inaoka, Sirius. Extensive osteonecrosis of the maxilla caused by bisphosphonates : report of a rare case. En: Journal of Clinical and Experimental Dentistry, 11 2 2019: 203-207 es
dc.title Extensive osteonecrosis of the maxilla caused by bisphosphonates : report of a rare case es
dc.type info:eu-repo/semantics/article en
dc.type info:eu-repo/semantics/publishedVersion en
dc.subject.unesco UNESCO::CIENCIAS MÉDICAS es
dc.identifier.doi 10.4317/jced.55151 es

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